%0 Journal Article
%A Buchholz, Martin
%A Spahn, Ingo
%A Coenen, Heinrich Hubert
%T Optimized separation procedure for production of no-carrier-added radiomanganese for positron emission tomography
%J Radiochimica acta
%V 103
%N 12
%@ 2193-3405
%C Berlin
%I De Gruyter
%M FZJ-2017-06369
%P 7
%D 2015
%X The natCr(p, xn)-process is a very efficient route for production of 52gMn (T1/2 = 5.59 d). Based on measurements of distribution coefficients with different media and ion-exchange resins, an optimized chromatographic separation of radiomanganese from natCr with the resin Amberlite CG400 was developed. With this system natCr is eluted first with an acetic acid/methanol 1:1 mixture at room temperature and 52gMn thereafter with 3 M HCl at 50 ℃. Within a separation time of 4 h the method yielded 99.5% of the n.c.a. 52gMn in 2–3 mL of 3 M HCl. An ICP-MS analysis revealed a chromium impurity of 0.07 mg (0.014%) in the n.c.a. 52gMn solution, making this separation method suitable for the production of 52gMn for medical applications like positron emission tomography (PET).
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000366187300008
%R 10.1515/ract-2015-2506
%U https://juser.fz-juelich.de/record/837456