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@ARTICLE{Buchholz:837456,
author = {Buchholz, Martin and Spahn, Ingo and Coenen, Heinrich
Hubert},
title = {{O}ptimized separation procedure for production of
no-carrier-added radiomanganese for positron emission
tomography},
journal = {Radiochimica acta},
volume = {103},
number = {12},
issn = {2193-3405},
address = {Berlin},
publisher = {De Gruyter},
reportid = {FZJ-2017-06369},
pages = {7},
year = {2015},
abstract = {The natCr(p, xn)-process is a very efficient route for
production of 52gMn (T1/2 = 5.59 d). Based on
measurements of distribution coefficients with different
media and ion-exchange resins, an optimized chromatographic
separation of radiomanganese from natCr with the resin
Amberlite CG400 was developed. With this system natCr is
eluted first with an acetic acid/methanol 1:1 mixture at
room temperature and 52gMn thereafter with 3 M HCl at
50 ℃. Within a separation time of 4 h the method
yielded $99.5\%$ of the n.c.a. 52gMn in 2–3 mL of 3 M
HCl. An ICP-MS analysis revealed a chromium impurity of
0.07 mg $(0.014\%)$ in the n.c.a. 52gMn solution, making
this separation method suitable for the production of 52gMn
for medical applications like positron emission tomography
(PET).},
cin = {INM-5},
ddc = {540},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000366187300008},
doi = {10.1515/ract-2015-2506},
url = {https://juser.fz-juelich.de/record/837456},
}