TY  - JOUR
AU  - Bachmann, Bernd
AU  - Adly, Nouran
AU  - Schnitker, Jan
AU  - Yakushenko, Alexey
AU  - Rinklin, Philipp
AU  - Offenhäusser, Andreas
AU  - Wolfrum, Bernhard
TI  - All-inkjet-printed gold microelectrode arrays for extracellular recording of action potentials
JO  - Physics world
VL  - 2
IS  - 3
SN  - 2058-8585
CY  - Bristol
PB  - IOP Publ.
M1  - FZJ-2017-06421
SP  - 035003 -
PY  - 2017
AB  - Inkjet printing is an attractive method for cost-effective additive manufacturing of electronic devices. Especially for applications where disposable sensor systems are of interest, it is a promising tool since it enables the production of low-cost and flexible devices. In this work, we report the fabrication of a disposable microelectrode array (MEA) using solely inkjet printing technology. The MEAs were fabricated with two different functional inks, a self-made gold ink to print conductive feedlines and electrodes and a polymer-based ink to add a dielectric layer for insulation of the feedlines. We printed different MEA designs of up to 64 electrodes with a minimum lateral spacing of 200 μm and a minimum electrode diameter of ~31 μm. As a proof-of-concept, extracellular recordings of action potentials from cardiomyocyte-like HL-1 cells were performed using the all-printed devices. Furthermore, we stimulated the cells during the recordings with noradrenaline, which led to an increase in the recorded beating frequency of the cells. The results demonstrate the feasibility of inkjet printing gold MEAs for cell-based bioelectronics.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000410630500005
DO  - DOI:10.1088/2058-8585/aa7928
UR  - https://juser.fz-juelich.de/record/837533
ER  -