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@ARTICLE{Jin:837943,
      author       = {Jin, Lei and Jin, Lei and Yu, Jingru and Xu, Yanjun and
                      Liu, Hui and Ren, Aiguo},
      title        = {{P}revalence of {N}eural {T}ube {D}efects and the {I}mpact
                      of {P}renatal {D}iagnosis in {T}hree {D}istricts of
                      {B}eijing, {C}hina},
      journal      = {Paediatric and perinatal epidemiology},
      volume       = {31},
      number       = {4},
      issn         = {0269-5022},
      address      = {Oxford [u.a.]},
      publisher    = {Wiley-Blackwell},
      reportid     = {FZJ-2017-06704},
      pages        = {293 - 300},
      year         = {2017},
      abstract     = {BackgroundThe objectives of this study were to explore the
                      prevalence of neural tube defects (NTDs) in three districts
                      of Beijing, and to evaluate the impact of prenatal diagnosis
                      on the prevalence.MethodsData were collected between 2006
                      and 2012 from the Beijing Birth Defects Surveillance System.
                      P13 and P28 represent the prevalence of NTDs diagnosed from
                      13 weeks and 28 weeks of gestation, respectively, to 7 days
                      after delivery. Populations were classified as household
                      (permanent) and non-household (non-permanent) because
                      differences exist in access to health care, education, and
                      income, among others.ResultsThe P13 of NTDs was 11.7 per 10
                      000 births in the three districts, which declined from
                      2006–12. In addition, the prevalence of NTDs in the
                      non-household population was 1.7-fold higher than that among
                      the household population. The P13 of anencephaly, spina
                      bifida, and encephalocele were 5.3, 4.9, 1.6, respectively,
                      per 10 000 births. The P28 of NTDs only represented $29.1\%$
                      of P13, and this proportion decreased over the 7-year
                      period.ConclusionsThe prevalence of NTDs remains high in the
                      three districts of Beijing, and the rate was higher in the
                      non-household than household population. The prevalence of
                      birth defects would be under estimated by almost 70 per cent
                      if the report time was set on 28 weeks’ gestation or later
                      compared with report time on 13 weeks of gestation. It is
                      better to set the report time earlier in birth defect
                      surveillance in contemporary China.},
      cin          = {ER-C-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)ER-C-1-20170209},
      pnm          = {143 - Controlling Configuration-Based Phenomena (POF3-143)},
      pid          = {G:(DE-HGF)POF3-143},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000405827300007},
      doi          = {10.1111/ppe.12354},
      url          = {https://juser.fz-juelich.de/record/837943},
}