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@ARTICLE{Fu:838721,
      author       = {Fu, Wangyang and Feng, Lingyan and Panaitov, Gregory and
                      Kireev, Dmitry and Mayer, Dirk and Offenhäusser, Andreas
                      and Krause, Hans-Joachim},
      title        = {{B}iosensing near the neutrality point of graphene},
      journal      = {Science advances},
      volume       = {3},
      number       = {10},
      issn         = {2375-2548},
      address      = {Washington, DC [u.a.]},
      publisher    = {Assoc.},
      reportid     = {FZJ-2017-07281},
      pages        = {e1701247 -},
      year         = {2017},
      abstract     = {Over the past decade, the richness of electronic properties
                      of graphene has attracted enormous interest for electrically
                      detecting chemical and biological species using this
                      two-dimensional material. However, the creation of practical
                      graphene electronic sensors greatly depends on our ability
                      to understand and maintain a low level of electronic noise,
                      the fundamental reason limiting the sensor resolution.
                      Conventionally, to reach the largest sensing response,
                      graphene transistors are operated at the point of maximum
                      transconductance, where 1/f noise is found to be unfavorably
                      high and poses a major limitation in any attempt to further
                      improve the device sensitivity. We show that operating a
                      graphene transistor in an ambipolar mode near its neutrality
                      point can markedly reduce the 1/f noise in graphene.
                      Remarkably, our data reveal that this reduction in the
                      electronic noise is achieved with uncompromised sensing
                      response of the graphene chips and thus significantly
                      improving the signal-to-noise ratio—compared to that of a
                      conventionally operated graphene transistor for conductance
                      measurement. As a proof-of-concept demonstration of the
                      usage of the aforementioned new sensing scheme to a broader
                      range of biochemical sensing applications, we selected an
                      HIV-related DNA hybridization as the test bed and achieved
                      detections at picomolar concentrations.},
      cin          = {ICS-8 / JARA-FIT},
      ddc          = {500},
      cid          = {I:(DE-Juel1)ICS-8-20110106 / $I:(DE-82)080009_20140620$},
      pnm          = {552 - Engineering Cell Function (POF3-552) / 553 - Physical
                      Basis of Diseases (POF3-553) / 523 - Controlling
                      Configuration-Based Phenomena (POF3-523)},
      pid          = {G:(DE-HGF)POF3-552 / G:(DE-HGF)POF3-553 /
                      G:(DE-HGF)POF3-523},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29075669},
      UT           = {WOS:000417998700028},
      doi          = {10.1126/sciadv.1701247},
      url          = {https://juser.fz-juelich.de/record/838721},
}