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| Home > Publications database > AIDS-Related Central Nervous System Toxoplasmosis With Increased 18F-Fluoroethyl-L-Tyrosine Amino Acid PET Uptake Due to LAT1/2 Expression of Inflammatory Cells > print |
| Home > Publications database > AIDS-Related Central Nervous System Toxoplasmosis With Increased 18F-Fluoroethyl-L-Tyrosine Amino Acid PET Uptake Due to LAT1/2 Expression of Inflammatory Cells > print |
| 001 | 838850 | ||
| 005 | 20210129231644.0 | ||
| 024 | 7 | _ | |a 10.1097/RLU.0000000000001873 |2 doi |
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| 100 | 1 | _ | |a Hutterer, Markus |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a AIDS-Related Central Nervous System Toxoplasmosis With Increased 18F-Fluoroethyl-L-Tyrosine Amino Acid PET Uptake Due to LAT1/2 Expression of Inflammatory Cells |
| 260 | _ | _ | |a Philadelphia, Pa. |c 2017 |b Lippincott Williams & Wilkins |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
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| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a We report the case of a 40-year-old woman with a progressive right-sided hemiparesis. Standard MRI revealed a contrast-enhancing brain lesion within the left basal ganglia. 18Ffluoroethyl-L-tyrosine (18F-FET) PET showed a distinct tracer uptake (lesion-to-brain ratio [LBR]: LBRmax = 2.03, LBRmean = 1.68) with a significant larger metabolic lesion volume than contrast-enhancement in MRI, indicating cerebral glioma. Surprisingly, histopathologic analysis demonstrated central nervous system toxoplasmosis with pronounced inflammatory reaction (reactive astrogliosis, microglia activation, macrophage, and T-lymphocyte infiltration), which was associated with strong LAT1/LAT2/CD98 expression. In conclusion, inflammatory brain lesions, such as cerebral toxoplasmosis, represent a potential pitfall of 18F-FET PET mimicking a brain tumor. |
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| 700 | 1 | _ | |a Riemenschneider, Markus J. |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Grosse, Jirka |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Hellwig, Dirk |0 P:(DE-HGF)0 |b 4 |
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| 700 | 1 | _ | |a Hau, Peter |0 P:(DE-HGF)0 |b 7 |
| 773 | _ | _ | |a 10.1097/RLU.0000000000001873 |g Vol. 42, no. 12, p. e506 - e508 |0 PERI:(DE-600)2045053-9 |n 12 |p e506 - e508 |t Clinical nuclear medicine |v 42 |y 2017 |x 0363-9762 |
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