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@ARTICLE{Eicher:838852,
      author       = {Eicher, Barbara and Heberle, Frederick A. and Marquardt,
                      Drew and Rechberger, Gerald N. and Katsaras, John and Pabst,
                      Georg},
      title        = {{J}oint small-angle {X}-ray and neutron scattering data
                      analysis of asymmetric lipid vesicles},
      journal      = {Journal of applied crystallography},
      volume       = {50},
      number       = {2},
      issn         = {1600-5767},
      address      = {Copenhagen},
      publisher    = {Munksgaard},
      reportid     = {FZJ-2017-07362},
      pages        = {419 - 429},
      year         = {2017},
      abstract     = {Low- and high-resolution models describing the internal
                      transbilayer structure of asymmetric lipid vesicles have
                      been developed. These models can be used for the joint
                      analysis of small-angle neutron and X-ray scattering data.
                      The models describe the underlying scattering length
                      density/electron density profiles either in terms of slabs
                      or through the so-called scattering density profile,
                      previously applied to symmetric lipid vesicles. Both models
                      yield structural details of asymmetric membranes, such as
                      the individual area per lipid, and the hydrocarbon thickness
                      of the inner and outer bilayer leaflets. The scattering
                      density profile model, however, comes at a cost of increased
                      computational effort but results in greater structural
                      resolution, showing a slightly lower packing of lipids in
                      the outer bilayer leaflet of ∼120 nm diameter
                      palmitoyl­oleoyl phosphatidyl­choline (POPC) vesicles,
                      compared to the inner leaflet. Analysis of asymmetric
                      dipalmitoyl phosphatidylcholine/POPC vesicles did not reveal
                      evidence of transbilayer coupling between the inner and
                      outer leaflets at 323 K, i.e. above the melting transition
                      temperature of the two lipids.},
      cin          = {JCNS (München) ; Jülich Centre for Neutron Science JCNS
                      (München) ; JCNS-FRM-II},
      ddc          = {540},
      cid          = {I:(DE-Juel1)JCNS-FRM-II-20110218},
      pnm          = {6G15 - FRM II / MLZ (POF3-6G15) / 6G4 - Jülich Centre for
                      Neutron Research (JCNS) (POF3-623)},
      pid          = {G:(DE-HGF)POF3-6G15 / G:(DE-HGF)POF3-6G4},
      experiment   = {EXP:(DE-MLZ)KWS1-20140101},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28381971},
      UT           = {WOS:000399010000010},
      doi          = {10.1107/S1600576717000656},
      url          = {https://juser.fz-juelich.de/record/838852},
}