000838939 001__ 838939
000838939 005__ 20210129231700.0
000838939 0247_ $$2doi$$a10.1038/s41598-017-15582-4
000838939 0247_ $$2Handle$$a2128/16123
000838939 0247_ $$2pmid$$apmid:29127413
000838939 0247_ $$2WOS$$aWOS:000414917800079
000838939 0247_ $$2altmetric$$aaltmetric:30028756
000838939 037__ $$aFZJ-2017-07442
000838939 041__ $$aEnglish
000838939 082__ $$a000
000838939 1001_ $$00000-0001-5151-7710$$aPeters, J.$$b0$$eCorresponding author
000838939 245__ $$aThermodynamics of lipid multi-lamellar vesicles in presence of sterols at high hydrostatic pressure
000838939 260__ $$aLondon$$bNature Publishing Group$$c2017
000838939 3367_ $$2DRIVER$$aarticle
000838939 3367_ $$2DataCite$$aOutput Types/Journal article
000838939 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1512476795_31845
000838939 3367_ $$2BibTeX$$aARTICLE
000838939 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000838939 3367_ $$00$$2EndNote$$aJournal Article
000838939 520__ $$aWe compared the effect of cholesterol at different concentration on the phase behaviour of DMPC(1,2-dimyristoyl-sn-glycero-3-phosphocholine) multilamellar vesicles. We used pressure perturbationdifferential scanning calorimetry (PPC) that studies a system on the whole by giving access to relevantthermodynamic quantities, and elastic incoherent neutron scattering (EINS) that probes local motionsof a system at the atomic level by allowing extraction of dynamical parameters. PPC revealed thatthe volume expansion coefficient of DMPC and DMPC/Cholesterol samples with 13 and 25 mol%cholesterol is a linear function of the heat capacity measured by differential scanning calorimetry.Neutron backscattering spectroscopy showed that the mean square displacements of H atoms doexhibit an increase with temperature and a decrease under increasing pressure. Cholesterol added atconcentrations of 25 and 50 mol% led to suppression of the main phase transition. Taking advantage ofthese results, the present study aims (i) to show that calorimetry and EINS using the Bicout and Zaccaimodel equally permit to get access to thermodynamic quantities characterizing pure DMPC and DMPC/cholesterol mixtures, thus directly confirming the theoretical method, and (ii) to validate our approachas function of temperature and of pressure, as both are equally important and complementarythermodynamic variables.
000838939 536__ $$0G:(DE-HGF)POF3-6G4$$a6G4 - Jülich Centre for Neutron Research (JCNS) (POF3-623)$$cPOF3-623$$fPOF III$$x0
000838939 536__ $$0G:(DE-HGF)POF3-6G15$$a6G15 - FRM II / MLZ (POF3-6G15)$$cPOF3-6G15$$fPOF III$$x1
000838939 588__ $$aDataset connected to CrossRef
000838939 65027 $$0V:(DE-MLZ)SciArea-160$$2V:(DE-HGF)$$aBiology$$x0
000838939 65017 $$0V:(DE-MLZ)GC-130-2016$$2V:(DE-HGF)$$aHealth and Life$$x0
000838939 693__ $$0EXP:(DE-MLZ)NOSPEC-20140101$$5EXP:(DE-MLZ)NOSPEC-20140101$$eNo specific instrument$$x0
000838939 7001_ $$0P:(DE-HGF)0$$aMarion, J.$$b1
000838939 7001_ $$0P:(DE-HGF)0$$aBecher, F. J.$$b2
000838939 7001_ $$0P:(DE-HGF)0$$aTrapp, M.$$b3
000838939 7001_ $$0P:(DE-Juel1)168124$$aGutberlet, T.$$b4$$ufzj
000838939 7001_ $$00000-0003-0750-997X$$aBicout, D. J.$$b5
000838939 7001_ $$00000-0003-4599-4582$$aHeimburg, T.$$b6
000838939 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/s41598-017-15582-4$$gVol. 7, no. 1, p. 15339$$n1$$p15339$$tScientific reports$$v7$$x2045-2322$$y2017
000838939 8564_ $$uhttps://juser.fz-juelich.de/record/838939/files/s41598-017-15582-4.pdf$$yOpenAccess
000838939 8564_ $$uhttps://juser.fz-juelich.de/record/838939/files/s41598-017-15582-4.gif?subformat=icon$$xicon$$yOpenAccess
000838939 8564_ $$uhttps://juser.fz-juelich.de/record/838939/files/s41598-017-15582-4.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess
000838939 8564_ $$uhttps://juser.fz-juelich.de/record/838939/files/s41598-017-15582-4.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
000838939 8564_ $$uhttps://juser.fz-juelich.de/record/838939/files/s41598-017-15582-4.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
000838939 8564_ $$uhttps://juser.fz-juelich.de/record/838939/files/s41598-017-15582-4.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000838939 909CO $$ooai:juser.fz-juelich.de:838939$$pdnbdelivery$$pVDB$$popen_access$$pdriver$$pVDB:MLZ$$popenaire
000838939 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)168124$$aForschungszentrum Jülich$$b4$$kFZJ
000838939 9131_ $$0G:(DE-HGF)POF3-623$$1G:(DE-HGF)POF3-620$$2G:(DE-HGF)POF3-600$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF3-6G4$$aDE-HGF$$bForschungsbereich Materie$$lVon Materie zu Materialien und Leben$$vFacility topic: Neutrons for Research on Condensed Matter$$x0
000838939 9131_ $$0G:(DE-HGF)POF3-6G15$$1G:(DE-HGF)POF3-6G0$$2G:(DE-HGF)POF3-600$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF3-6G15$$aDE-HGF$$bForschungsbereich Materie$$lGroßgeräte: Materie$$vFRM II / MLZ$$x1
000838939 9141_ $$y2017
000838939 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000838939 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000838939 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000838939 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record
000838939 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bSCI REP-UK : 2015
000838939 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bSCI REP-UK : 2015
000838939 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal
000838939 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ
000838939 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000838939 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000838939 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000838939 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000838939 915__ $$0StatID:(DE-HGF)1150$$2StatID$$aDBCoverage$$bCurrent Contents - Physical, Chemical and Earth Sciences
000838939 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000838939 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000838939 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List
000838939 9201_ $$0I:(DE-Juel1)JCNS-FRM-II-20110218$$kJCNS (München) ; Jülich Centre for Neutron Science JCNS (München) ; JCNS-FRM-II$$lJCNS-FRM-II$$x0
000838939 9201_ $$0I:(DE-Juel1)JCNS-1-20110106$$kNeutronenstreuung ; JCNS-1$$lNeutronenstreuung $$x1
000838939 9201_ $$0I:(DE-Juel1)JCNS-2-20110106$$kJCNS-2$$lStreumethoden$$x2
000838939 980__ $$ajournal
000838939 980__ $$aVDB
000838939 980__ $$aUNRESTRICTED
000838939 980__ $$aI:(DE-Juel1)JCNS-FRM-II-20110218
000838939 980__ $$aI:(DE-Juel1)JCNS-1-20110106
000838939 980__ $$aI:(DE-Juel1)JCNS-2-20110106
000838939 9801_ $$aFullTexts