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@INPROCEEDINGS{Sprenger:840027,
author = {Sprenger, Julia and Yegenoglu, Alper and Grün, Sonja and
Denker, Michael},
title = {{M}anagement of data and metadata - an exemplary
electrophysiological workflow for collaborative data
analysis},
reportid = {FZJ-2017-07593},
year = {2017},
abstract = {The complexity of neuroscientific experiments and their
analysis has grown to a degree where special effort
andattention is required to guarantee their reproducibility.
In addition, collaborations across different laboratoriesand
countries are becoming a standard work setting, which
increases the need for comprehensivedocumentation of data
and metadata, and explicit, formal descriptions of the data
analysis process. Theavailability of software tools that
support scientists in the various steps of this process is
therefore indispensable[Denker and Grün (2016) In:
Brain-Inspired Computing: Brain Comp 2015, Springer].
Moreover, it is necessary toestablish the workflows that
link the various tools, and to develop simple interfaces for
them.Here we demonstrate how such a reproducible,
structured, and comprehensible workflow for
anelectrophysiological experiment, covering the preparation,
annotation and analysis data, can be set up in
acollaborative environment by the combination of multiple
state-of-the-art open-source projects. The workflowfeatures
the Electrophysiology Analysis Toolkit (Elephant), which
represents the central analysis resourceoffering methods
ranging from the analysis of ensemble spike data to
population signals, such as local fieldpotentials
[http://neuralensemble.org/elephant/]. Elephant is based on
the generic standardized datarepresentation for
electrophysiological data provided by the Neo library
[Garcia et al. (2014) Front Neuroinf8:10]. In addition, Neo
is able to interface with a range of data formats commonly
used in electrophysiology. Theopen metadata Markup Language
(odML) is used as the hierarchical structure to store
metadata related toelectrophysiological experiments [Grewe
et al. (2011) Front Neuroinf 5:16]. Furthermore, odMLtables
extendsthe accessibility of odML by providing an interface
to a tabular metadata representation, e.g., using
Excel[https://github.com/INM-6/python-odmltables]. Finally,
NIX is a newly developed scheme designed to
combineelectrophysiological data and metadata in a single,
standardized format [https://github.com/G-Node/nix],
andlinks the Neo and odML data models. We discuss multiple
mechanisms that allow to describe the workflow itself,and
show how it may be implemented, e.g., using the
Collaboratory of the Human Brain
Project[https://collab.humanbrainproject.eu]. While focusing
on electrophysiology, many concepts of this workflow arealso
transferable to different types of experimental
environments.},
month = {Nov},
date = {2017-11-11},
organization = {The 47th annual meeting of the Society
for Neuroscience, Washington DC (USA),
11 Nov 2017 - 15 Nov 2017},
subtyp = {After Call},
cin = {INM-10 / INM-6 / IAS-6},
cid = {I:(DE-Juel1)INM-10-20170113 / I:(DE-Juel1)INM-6-20090406 /
I:(DE-Juel1)IAS-6-20130828},
pnm = {571 - Connectivity and Activity (POF3-571) / SMHB -
Supercomputing and Modelling for the Human Brain
(HGF-SMHB-2013-2017) / HBP SGA1 - Human Brain Project
Specific Grant Agreement 1 (720270) / DFG project 238707842
- Kausative Mechanismen mesoskopischer Aktivitätsmuster in
der auditorischen Kategorien-Diskrimination (238707842) /
DFG project 237833830 - Optogenetische Analyse der für
kognitive Fähigkeiten zuständigen
präfrontal-hippokampalen Netzwerke in der Entwicklung
(237833830) / DFG project 238707842 - Kausative Mechanismen
mesoskopischer Aktivitätsmuster in der auditorischen
Kategorien-Diskrimination (238707842)},
pid = {G:(DE-HGF)POF3-571 / G:(DE-Juel1)HGF-SMHB-2013-2017 /
G:(EU-Grant)720270 / G:(GEPRIS)238707842 /
G:(GEPRIS)237833830 / G:(GEPRIS)238707842},
typ = {PUB:(DE-HGF)24},
url = {https://juser.fz-juelich.de/record/840027},
}