TY  - JOUR
AU  - Spahn, Ingo
AU  - Qaim, Syed M.
TI  - Development of novel radionuclides for medical applications 
JO  - Journal of labelled compounds and radiopharmaceuticals
VL  - 61
SN  - 0362-4803
CY  - New York, NY [u.a.]
PB  - Wiley
M1  - FZJ-2017-07881
SP  - 126-140
PY  - 2018
AB  - Medical radionuclide production technology is well established. There is, however, a constant need for further development of radionuclides. The present efforts are mainly devoted to non-standard positron emitters (e.g. 64Cu, 86Y, 124I, 73Se) and novel therapeutic radionuclides emitting low-range β- particles (e. g. 67Cu, 186Re), conversion or Auger electrons (e.g. 117mSn, 77Br) and α-particles (e.g. 225Ac). A brief account of various aspects of development work (i.e. nuclear data, targetry, chemical processing, quality control) is given. For each radionuclide under consideration the status of technology for clinical scale production is discussed. The increasing need of intermediate-energy multiple-particle accelerating cyclotrons is pointed out.
LB  - PUB:(DE-HGF)16
C6  - pmid:29110328
UR  - <Go to ISI:>//WOS:000428647600003
DO  - DOI:10.1002/jlcr.3578
UR  - https://juser.fz-juelich.de/record/840339
ER  -