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@ARTICLE{Morschett:841203,
      author       = {Morschett, Holger and Loomba, Varun and Huber, Gregor and
                      Wiechert, Wolfgang and von Lieres, Eric and Oldiges, Marco},
      title        = {{L}aboratory scale photobiotechnology – {C}urrent trends
                      and future perspectives},
      journal      = {FEMS microbiology letters},
      volume       = {365},
      number       = {1},
      issn         = {1574-6968},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {FZJ-2017-08296},
      pages        = {1-9},
      year         = {2018},
      abstract     = {Phototrophic bioprocesses are a promising puzzle piece in
                      future bioeconomy concepts but yet mostly fail for economic
                      reasons. Besides other aspects, this is mainly attributed to
                      the omnipresent issue of optimal light supply impeding
                      scale-up and -down of phototrophic processes according to
                      classic established concepts. This MiniReview examines two
                      current trends in photobiotechnology, namely microscale
                      cultivation and modeling and simulation.
                      Microphotobioreactors are a valuable and promising trend
                      with microfluidic chips and microtiter plates as predominant
                      design concepts. Providing idealized conditions, chip
                      systems are preferably to be used for acquiring
                      physiological data of microalgae while microtiter plate
                      systems are more appropriate for process parameter and
                      medium screenings. However, these systems are far from
                      series technology and significant improvements especially
                      regarding flexible light supply remain crucial. Whereas
                      microscale is less addressed by modeling and simulation so
                      far, benchtop photobioreactor design and operation have
                      successfully been studied using such tools. This
                      particularly includes quantitative model-assisted
                      understanding of mixing, mass transfer, light dispersion and
                      particle tracing as well as their relevance for microalgal
                      performance. The ultimate goal will be to combine
                      physiological data from microphotobioreactors with hybrid
                      models to integrate metabolism and reactor simulation in
                      order to facilitate knowledge-based scale transfer of
                      phototrophic bioprocesses.},
      cin          = {IBG-1 / IBG-2},
      ddc          = {570},
      cid          = {I:(DE-Juel1)IBG-1-20101118 / I:(DE-Juel1)IBG-2-20101118},
      pnm          = {583 - Innovative Synergisms (POF3-583)},
      pid          = {G:(DE-HGF)POF3-583},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000428748700001},
      doi          = {10.1093/femsle/fnx238},
      url          = {https://juser.fz-juelich.de/record/841203},
}