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000841289 1001_ $$0P:(DE-HGF)0$$aOrtega, Jose Antonio$$b0
000841289 245__ $$aPharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity
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000841289 520__ $$aWe used a pharmacophore hybridization strategy to combine key structural elements of merbarone and etoposide and generated new type II topoisomerase (topoII) poisons. This first set of hybrid topoII poisons shows promising antiproliferative activity on human cancer cells, endorsing their further exploration for anticancer drug discovery.
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000841289 7001_ $$0P:(DE-HGF)0$$aRiccardi, Laura$$b1
000841289 7001_ $$0P:(DE-HGF)0$$aMinniti, Elirosa$$b2
000841289 7001_ $$0P:(DE-HGF)0$$aBorgogno, Marco$$b3
000841289 7001_ $$00000-0003-3227-931X$$aArencibia, Jose M.$$b4
000841289 7001_ $$0P:(DE-HGF)0$$aGreco, Maria L.$$b5
000841289 7001_ $$0P:(DE-HGF)0$$aMinarini, Anna$$b6
000841289 7001_ $$00000-0002-9713-1415$$aSissi, Claudia$$b7$$eCorresponding author
000841289 7001_ $$00000-0003-4022-5661$$aDe Vivo, Marco$$b8$$eCorresponding author
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