%0 Journal Article
%A Kusen, Peter M.
%A Hoffmann, Kyra
%A Wandrey, Georg
%A Büchs, Jochen
%A Pietruszka, Jörg
%T Optische Genregulation in Mikrobioreaktoren
%J Biospektrum
%V 23
%N 6
%@ 0947-0867
%C Heidelberg
%I Spektrum
%M FZJ-2018-00136
%P 643-645
%D 2017
%X Photolabile-caged effector molecules allow non-invasive regulation of gene expression using cell-compatible UVA-irradiation. Based on this method, independent photoregulation of gene expression was combined with optical online monitoring of important cultivation parameters in a 48-well plate format. Thereby, an innovative screening system was created which allows for cost-effective and easily automated expression profiling as well as closed-loop process control.
%F PUB:(DE-HGF)16
%9 Journal Article
%R 10.1007/s12268-017-0850-0
%U https://juser.fz-juelich.de/record/841835