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@ARTICLE{Worgull:841836,
author = {Worgull, Dennis and Öhler, Laura and Strache, Joss Pepe
and Friedrichs, Teresa and Ullrich, Patrick},
title = {{E}nantioselective {S}ynthesis of 2,3-{D}ihydrofurans via
{A}mmonium {Y}lides},
journal = {European journal of organic chemistry},
volume = {2017},
number = {40},
issn = {1434-193X},
address = {Weinheim},
publisher = {Wiley-VCH Verl.},
reportid = {FZJ-2018-00137},
pages = {6077 - 6080},
year = {2017},
abstract = {A chiral, ammonium ylide based access to tetrasubstituted
2,3-dihydrofurans starting from readily available
benzylidene dicarbonyls and bromo acetophenones has been
developed. The products are obtained in moderate to good
yields with excellent diasteroselectivity and good to
excellent enantioselectivity (up to 99:1 e.r.). The employed
chiral amine can be recovered in near quantitative yield.
The transformation can be run as a three-component one-pot
reaction, generating the ammonium salt and ylide in situ.
The scope of this reaction includes 17 new dihydrofurans
with aromatic or heteroaromatic substituents.},
cin = {IBOC / IBG-1},
ddc = {540},
cid = {I:(DE-Juel1)IBOC-20090406 / I:(DE-Juel1)IBG-1-20101118},
pnm = {581 - Biotechnology (POF3-581)},
pid = {G:(DE-HGF)POF3-581},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000414341700015},
doi = {10.1002/ejoc.201701176},
url = {https://juser.fz-juelich.de/record/841836},
}