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@ARTICLE{Schnitker:842343,
author = {Schnitker, Jan and Adly, Nouran and Seyock, Silke and
Bachmann, Bernd and Yakushenko, Alexey and Wolfrum, Bernhard
and Offenhäusser, Andreas},
title = {{R}apid {P}rototyping of {U}ltralow-{C}ost,
{I}nkjet-{P}rinted {C}arbon {M}icroelectrodes for {F}lexible
{B}ioelectronic {D}evices},
journal = {Advanced biosystems},
volume = {2},
number = {3},
issn = {2366-7478},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {FZJ-2018-00585},
pages = {1700136 -},
year = {2018},
abstract = {Gaining better understanding of the human brain using
chip‐based devices and promoting the recovery of lost
biological functionality through implants are long pursued
endeavors driven by advances in material science,
bioelectronics, and the advancing silicon technology. While
conventional bioelectronic and neuroelectronic devices
typically rely on cleanroom‐based processing, a rapid
prototyping technique is proposed that is based on
high‐resolution inkjet printing featuring nanoporous
carbon electrodes that yield excellent cell–chip coupling.
This study aims to overcome two major limitations of
conventional approaches that make the development of
neuroelectronic devices very challenging and limit a wider
use within the research community as well as industry: high
costs and lack of rapid prototyping capabilities. These
challenges are addressed with an all‐printed,
high‐resolution approach that makes use of flexible
polymer substrates and is fabricated on a fully digital
printing platform. The manufacturing of a chip consumes less
than 60 min and costs a few cents per chip. This study
introduces nanoporous carbon as a cell‐interfacing
electrode material that features outstanding properties for
extracellular recording of action potentials and stimulation
indicating that the printed carbon chips have the means to
be used as a versatile neuroelectronic tool for in vitro and
in vivo studies.},
cin = {ICS-8},
ddc = {570},
cid = {I:(DE-Juel1)ICS-8-20110106},
pnm = {552 - Engineering Cell Function (POF3-552)},
pid = {G:(DE-HGF)POF3-552},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000446968000002},
doi = {10.1002/adbi.201700136},
url = {https://juser.fz-juelich.de/record/842343},
}