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@ARTICLE{Lerche:843633,
      author       = {Lerche, Christoph W and Kaltsas, Theodoris and Caldeira,
                      Liliana and Scheins, Jürgen and Rota Kops, Elena and
                      Tellmann, Lutz and Pietrzyk, Uwe and Herzog, Hans and Shah,
                      N. J.},
      title        = {{PET} attenuation correction for rigid {MR} {T}x/{R}x coils
                      from 176 {L}u background activity},
      journal      = {Physics in medicine and biology},
      volume       = {63},
      number       = {3},
      issn         = {1361-6560},
      address      = {Bristol},
      publisher    = {IOP Publ.},
      reportid     = {FZJ-2018-01211},
      pages        = {035039 -},
      year         = {2018},
      abstract     = {One challenge for PET-MR hybrid imaging is the correction
                      for attenuation of the 511 keV annihilation radiation by
                      the required RF transmit and/or RF receive coils. Although
                      there are strategies for building PET transparent Tx/Rx
                      coils, such optimised coils still cause significant
                      attenuation of the annihilation radiation leading to
                      artefacts and biases in the reconstructed activity
                      concentrations. We present a straightforward method to
                      measure the attenuation of Tx/Rx coils in simultaneous
                      MR-PET imaging based on the natural 176Lu background
                      contained in the scintillator of the PET detector without
                      the requirement of an external CT scanner or PET scanner
                      with transmission source. The method was evaluated on a
                      prototype 3T MR-BrainPET produced by Siemens Healthcare
                      GmbH, both with phantom studies and with true emission
                      images from patient/volunteer examinations. Furthermore, the
                      count rate stability of the PET scanner and the x-ray
                      properties of the Tx/Rx head coil were investigated. Even
                      without energy extrapolation from the two dominant γ
                      energies of 176Lu to 511 keV, the presented method for
                      attenuation correction, based on the measurement of 176Lu
                      background attenuation, shows slightly better performance
                      than the coil attenuation correction currently used. The
                      coil attenuation correction currently used is based on an
                      external transmission scan with rotating 68Ge sources
                      acquired on a Siemens ECAT HR  +  PET scanner.
                      However, the main advantage of the presented approach is its
                      straightforwardness and ready availability without the need
                      for additional accessories.},
      cin          = {INM-4 / JARA-BRAIN},
      ddc          = {570},
      cid          = {I:(DE-Juel1)INM-4-20090406 / $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29408803},
      UT           = {WOS:000424367100001},
      doi          = {10.1088/1361-6560/aaa72a},
      url          = {https://juser.fz-juelich.de/record/843633},
}