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000844074 1001_ $$00000-0001-5760-6677$$aMilić, Dalibor$$b0
000844074 245__ $$aRecognition motif and mechanism of ripening inhibitory peptides in plant hormone receptor ETR1
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000844074 520__ $$aSynthetic peptides derived from ethylene-insensitive protein 2 (EIN2), a central regulator of ethylene signalling, were recently shown to delay fruit ripening by interrupting protein–protein interactions in the ethylene signalling pathway. Here, we show that the inhibitory peptide NOP-1 binds to the GAF domain of ETR1 – the prototype of the plant ethylene receptor family. Site-directed mutagenesis and computational studies reveal the peptide interaction site and a plausible molecular mechanism for the ripening inhibition.
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000844074 7001_ $$0P:(DE-HGF)0$$aDick, Markus$$b1
000844074 7001_ $$0P:(DE-HGF)0$$aMulnaes, Daniel$$b2
000844074 7001_ $$0P:(DE-HGF)0$$aPfleger, Christopher$$b3
000844074 7001_ $$0P:(DE-HGF)0$$aKinnen, Anna$$b4
000844074 7001_ $$0P:(DE-Juel1)172663$$aGohlke, Holger$$b5$$eCorresponding author
000844074 7001_ $$0P:(DE-HGF)0$$aGroth, Georg$$b6$$eCorresponding author
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