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@ARTICLE{Mili:844074,
author = {Milić, Dalibor and Dick, Markus and Mulnaes, Daniel and
Pfleger, Christopher and Kinnen, Anna and Gohlke, Holger and
Groth, Georg},
title = {{R}ecognition motif and mechanism of ripening inhibitory
peptides in plant hormone receptor {ETR}1},
journal = {Scientific reports},
volume = {8},
number = {1},
issn = {2045-2322},
address = {London},
publisher = {Nature Publishing Group},
reportid = {FZJ-2018-01583},
pages = {3890},
year = {2018},
abstract = {Synthetic peptides derived from ethylene-insensitive
protein 2 (EIN2), a central regulator of ethylene
signalling, were recently shown to delay fruit ripening by
interrupting protein–protein interactions in the ethylene
signalling pathway. Here, we show that the inhibitory
peptide NOP-1 binds to the GAF domain of ETR1 – the
prototype of the plant ethylene receptor family.
Site-directed mutagenesis and computational studies reveal
the peptide interaction site and a plausible molecular
mechanism for the ripening inhibition.},
cin = {JSC / NIC / ICS-6},
ddc = {000},
cid = {I:(DE-Juel1)JSC-20090406 / I:(DE-Juel1)NIC-20090406 /
I:(DE-Juel1)ICS-6-20110106},
pnm = {511 - Computational Science and Mathematical Methods
(POF3-511) / 574 - Theory, modelling and simulation
(POF3-574) / 582 - Plant Science (POF3-582) / BioSC -
Bioeconomy Science Center (BioSC) / Forschergruppe Gohlke
$(hkf7_20170501)$},
pid = {G:(DE-HGF)POF3-511 / G:(DE-HGF)POF3-574 /
G:(DE-HGF)POF3-582 / G:(DE-Juel1)BioSC /
$G:(DE-Juel1)hkf7_20170501$},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29497085},
UT = {WOS:000426354200062},
doi = {10.1038/s41598-018-21952-3},
url = {https://juser.fz-juelich.de/record/844074},
}