TY  - JOUR
AU  - GENON, Sarah
AU  - Reid, Andrew
AU  - Langner, Robert
AU  - Amunts, Katrin
AU  - Eickhoff, Simon
TI  - How to Characterize the Function of a Brain Region
JO  - Trends in cognitive sciences
VL  - 22
IS  - 4
SN  - 1364-6613
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - FZJ-2018-01623
SP  - 350-364
PY  - 2018
AB  - Many brain regions have been defined, but a comprehensive formalization of each region's function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of 'functions'. We briefly review these fields and outline how the heterogeneity of associations could be harnessed to disclose the computational function of any region. Aggregating activation data from neuroimaging studies allows us to characterize the functional engagement of a region across a range of experimental conditions. Furthermore, large-sample data can disclose covariation between brain region features and ecological behavioral phenotyping. Combining these two approaches opens a new perspective to determine the behavioral associations of a brain region, and hence its function and broader role within large-scale functional networks.
LB  - PUB:(DE-HGF)16
C6  - pmid:29501326
UR  - <Go to ISI:>//WOS:000428013800010
DO  - DOI:10.1016/j.tics.2018.01.010
UR  - https://juser.fz-juelich.de/record/844157
ER  -