% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Hammes:844289,
      author       = {Hammes, Jochen and Bischof, Gérard N. and Drzezga,
                      Alexander},
      title        = {{M}olecular imaging in early diagnosis, differential
                      diagnosis and follow-up of patients with neurodegenerative
                      diseases},
      journal      = {Clinical and translational imaging},
      volume       = {5},
      number       = {5},
      issn         = {2281-7565},
      address      = {Berlin},
      publisher    = {Springer Milan},
      reportid     = {FZJ-2018-01729},
      pages        = {465 - 471},
      year         = {2017},
      abstract     = {PurposeCurrent disease models suggest that many
                      neurodegenerative disorders are associated with pathological
                      protein aggregations that start to develop in the brain long
                      before the onset of clinical symptoms. Therefore, biomarkers
                      allowing early and reliable characterization of
                      neurodegenerative disease are required. Here we illustrate
                      the potential value of neuroimaging procedures by means of
                      selected examples.MethodsMultimodal imaging data of
                      exemplary patients who underwent FDG, Amyloid and
                      AV-1451-PET, FP-CIT-SPECT and MRI imaging in the routine
                      clinical workup in our department is presented and the
                      currently available literature on the topic of imaging in
                      neurodegenerative diseases was reviewed.ResultsThe
                      complementary value of the applied imaging methods is
                      demonstrated in pairs of representative cases. Depending on
                      the clinical question, individual methods or a meaningful
                      multimodal combination is required to achieve optimal
                      diagnostic benefit.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000411570700006},
      doi          = {10.1007/s40336-017-0242-y},
      url          = {https://juser.fz-juelich.de/record/844289},
}