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@ARTICLE{Nostro:845281,
author = {Nostro, Alessandra D. and Müller, Veronika and Varikuti,
Deepthi and Pläschke, Rachel and Hoffstaedter, Felix and
Langner, Robert and Patil, Kaustubh and Eickhoff, Simon},
title = {{P}redicting personality from network-based resting-state
functional connectivity},
journal = {Brain structure $\&$ function},
volume = {223},
number = {6},
issn = {1863-2661},
address = {Berlin},
publisher = {Springer},
reportid = {FZJ-2018-02562},
pages = {2699–2719},
year = {2018},
abstract = {Personality is associated with variation in all kinds of
mental faculties, including affective, social, executive,
and memory functioning. The intrinsic dynamics of neural
networks underlying these mental functions are reflected in
their functional connectivity at rest (RSFC). We, therefore,
aimed to probe whether connectivity in functional networks
allows predicting individual scores of the five-factor
personality model and potential gender differences thereof.
We assessed nine meta-analytically derived functional
networks, representing social, affective, executive, and
mnemonic systems. RSFC of all networks was computed in a
sample of 210 males and 210 well-matched females and in a
replication sample of 155 males and 155 females. Personality
scores were predicted using relevance vector machine in both
samples. Cross-validation prediction accuracy was defined as
the correlation between true and predicted scores. RSFC
within networks representing social, affective, mnemonic,
and executive systems significantly predicted self-reported
levels of Extraversion, Neuroticism, Agreeableness, and
Openness. RSFC patterns of most networks, however, predicted
personality traits only either in males or in females.
Personality traits can be predicted by patterns of RSFC in
specific functional brain networks, providing new insights
into the neurobiology of personality. However, as most
associations were gender-specific, RSFC–personality
relations should not be considered independently of gender.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {571 - Connectivity and Activity (POF3-571) / HBP SGA1 -
Human Brain Project Specific Grant Agreement 1 (720270)},
pid = {G:(DE-HGF)POF3-571 / G:(EU-Grant)720270},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29572625},
UT = {WOS:000434980400013},
doi = {10.1007/s00429-018-1651-z},
url = {https://juser.fz-juelich.de/record/845281},
}