%0 Journal Article
%A Kipping, Judy A.
%A Margulies, Daniel S.
%A Eickhoff, Simon
%A Lee, Annie
%A Qiu, Anqi
%T Trade-off of cerebello-cortical and cortico-cortical functional networks for planning in 6-year-old children
%J NeuroImage
%V 176
%@ 1053-8119
%C Orlando, Fla.
%I Academic Press
%M FZJ-2018-02927
%P 510-517
%D 2018
%X Childhood is a critical period for the development of cognitive planning. There is a lack of knowledge on its neural mechanisms in children. This study aimed to examine cerebello-cortical and cortico-cortical functional connectivity in association with planning skills in 6-year-olds (n = 76). We identified the cerebello-cortical and cortico-cortical functional networks related to cognitive planning using activation likelihood estimation (ALE) meta-analysis on existing functional imaging studies on spatial planning, and data-driven independent component analysis (ICA) of children's resting-state functional MRI (rs-fMRI). We investigated associations of cerebello-cortical and cortico-cortical functional connectivity with planning ability in 6-year-olds, as assessed using the Stockings of Cambridge task. Long-range functional connectivity of two cerebellar networks (lobules VI and lateral VIIa) with the prefrontal and premotor cortex were greater in children with poorer planning ability. In contrast, cortico-cortical association networks were not associated with the performance of planning in children. These results highlighted the key contribution of the lateral cerebello-frontal functional connectivity, but not cortico-cortical association functional connectivity, for planning ability in 6-year-olds. Our results suggested that brain adaptation to the acquisition of planning ability during childhood is partially achieved through the engagement of the cerebello-cortical functional connectivity.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29730492
%U <Go to ISI:>//WOS:000433223700043
%R 10.1016/j.neuroimage.2018.04.067
%U https://juser.fz-juelich.de/record/845715