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@ARTICLE{Kipping:845715,
author = {Kipping, Judy A. and Margulies, Daniel S. and Eickhoff,
Simon and Lee, Annie and Qiu, Anqi},
title = {{T}rade-off of cerebello-cortical and cortico-cortical
functional networks for planning in 6-year-old children},
journal = {NeuroImage},
volume = {176},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2018-02927},
pages = {510-517},
year = {2018},
abstract = {Childhood is a critical period for the development of
cognitive planning. There is a lack of knowledge on its
neural mechanisms in children. This study aimed to examine
cerebello-cortical and cortico-cortical functional
connectivity in association with planning skills in
6-year-olds (n = 76). We identified the
cerebello-cortical and cortico-cortical functional networks
related to cognitive planning using activation likelihood
estimation (ALE) meta-analysis on existing functional
imaging studies on spatial planning, and data-driven
independent component analysis (ICA) of children's
resting-state functional MRI (rs-fMRI). We investigated
associations of cerebello-cortical and cortico-cortical
functional connectivity with planning ability in
6-year-olds, as assessed using the Stockings of Cambridge
task. Long-range functional connectivity of two cerebellar
networks (lobules VI and lateral VIIa) with the prefrontal
and premotor cortex were greater in children with poorer
planning ability. In contrast, cortico-cortical association
networks were not associated with the performance of
planning in children. These results highlighted the key
contribution of the lateral cerebello-frontal functional
connectivity, but not cortico-cortical association
functional connectivity, for planning ability in
6-year-olds. Our results suggested that brain adaptation to
the acquisition of planning ability during childhood is
partially achieved through the engagement of the
cerebello-cortical functional connectivity.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {571 - Connectivity and Activity (POF3-571)},
pid = {G:(DE-HGF)POF3-571},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29730492},
UT = {WOS:000433223700043},
doi = {10.1016/j.neuroimage.2018.04.067},
url = {https://juser.fz-juelich.de/record/845715},
}