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@ARTICLE{Hartwigsen:845897,
author = {Hartwigsen, Gesa and Neef, Nicole E and Camilleri, Julia
and Margulies, Daniel S and Eickhoff, Simon},
title = {{F}unctional {S}egregation of the {R}ight {I}nferior
{F}rontal {G}yrus: {E}vidence {F}rom {C}oactivation-{B}ased
{P}arcellation},
journal = {Cerebral cortex},
volume = {29},
number = {4},
issn = {1460-2199},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {FZJ-2018-03096},
pages = {1532-1546},
year = {2019},
abstract = {Previous studies helped unraveling the functional
architecture of the human cerebral cortex. However, a
comprehensive functional segregation of right lateral
prefrontal cortex is missing. Here, we delineated cortical
clusters in right area 44 and 45 based on their
task-constrained whole-brain activation patterns across
neuroimaging experiments obtained from a large database. We
identified 5 clusters that differed with respect to their
coactivation patterns, which were consistent with
resting-state functional connectivity patterns of an
independent dataset. Two clusters in the posterior inferior
frontal gyrus (IFG) were functionally associated with action
inhibition and execution, while two anterior clusters were
related to reasoning and social cognitive processes. A fifth
cluster was associated with spatial attention. Strikingly,
the functional organization of the right IFG can thus be
characterized by a posterior-to-anterior axis with
action-related functions on the posterior and
cognition-related functions on the anterior end. We observed
further subdivisions along a dorsal-to-ventral axis in
posterior IFG between action execution and inhibition, and
in anterior IFG between reasoning and social cognition. The
different clusters were integrated in distinct large-scale
networks for various cognitive processes. These results
provide evidence for a general organization of cognitive
processes along axes spanning from more automatic to more
complex cognitive processes.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29912435},
UT = {WOS:000482180900011},
doi = {10.1093/cercor/bhy049},
url = {https://juser.fz-juelich.de/record/845897},
}