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@ARTICLE{Kutovyi:847917,
author = {Kutovyi, Y. and Zadorozhnyi, I. and Hlukhova, H. and
Handziuk, V. and Petrychuk, M. and Ivanchuk, Andriy and
Vitusevich, S.},
title = {{O}rigin of noise in liquid-gated {S}i nanowire troponin
biosensors},
journal = {Nanotechnology},
volume = {29},
number = {17},
issn = {1361-6528},
address = {Bristol},
publisher = {IOP Publ.},
reportid = {FZJ-2018-03238},
pages = {175202 -1-11},
year = {2018},
abstract = {Liquid-gated Si nanowire field-effect transistor (FET)
biosensors are fabricated using a complementary
metal-oxide-semiconductor-compatible top-down approach. The
transport and noise properties of the devices reflect the
high performance of the FET structures, which allows
label-free detection of cardiac troponin I (cTnI) molecules.
Moreover, after removing the troponin antigens the
structures demonstrate the same characteristics as before
cTnI detection, indicating the reusable operation of
biosensors. Our results show that the additional noise is
related to the troponin molecules and has characteristics
which considerably differ from those usually recorded for
conventional FETs without target molecules. We describe the
origin of the noise and suggest that noise spectroscopy
represents a powerful tool for understanding molecular
dynamic processes in nanoscale FET-based biosensors.},
cin = {ICS-8},
ddc = {530},
cid = {I:(DE-Juel1)ICS-8-20110106},
pnm = {523 - Controlling Configuration-Based Phenomena (POF3-523)},
pid = {G:(DE-HGF)POF3-523},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000426737300001},
pubmed = {pmid:29446349},
doi = {10.1088/1361-6528/aaaf9e},
url = {https://juser.fz-juelich.de/record/847917},
}