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@ARTICLE{Rosenberg:849856,
author = {Rosenberg, Jessica and Jacobs, Heidi I. L. and Maximov,
Ivan I. and Reske, Martina and Shah, N. J.},
title = {{C}hronotype differences in cortical thickness: grey matter
reflects when you go to bed},
journal = {Brain structure $\&$ function},
volume = {223},
number = {7},
issn = {1863-2661},
address = {Berlin},
publisher = {Springer},
reportid = {FZJ-2018-03958},
pages = {3411–3421},
year = {2018},
abstract = {Based on individual circadian cycles and associated
cognitive rhythms, humans can be classified via standardised
self-reports as being early (EC), late (LC) and intermediate
(IC) chronotypes. Alterations in neural cortical structure
underlying these chronotype differences have rarely been
investigated and are the scope of this study. 16 healthy
male ECs, 16 ICs and 16 LCs were measured with a 3 T
MAGNETOM TIM TRIO (Siemens, Erlangen) scanner using a
magnetization prepared rapid gradient echo sequence. Data
were analysed by applying voxel-based morphometry (VBM) and
vertex-wise cortical thickness (CTh) analysis. VBM analysis
revealed that ECs showed significantly lower grey matter
volumes bilateral in the lateral occipital cortex and the
precuneus as compared to LCs, and in the right lingual
gyrus, occipital fusiform gyrus and the occipital pole as
compared to ICs. CTh findings showed lower grey matter
volumes for ECs in the left anterior insula, precuneus,
inferior parietal cortex, and right pars triangularis than
for LCs, and in the right superior parietal gyrus than for
ICs. These findings reveal that chronotype differences are
associated with specific neural substrates of cortical
thickness, surface areas, and folding. We conclude that this
might be the basis for chronotype differences in behaviour
and brain function. Furthermore, our results speak for the
necessity of considering “chronotype” as a potentially
modulating factor in all kinds of structural brain-imaging
experiments.},
cin = {INM-3 / INM-4},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29948193},
UT = {WOS:000443296300023},
doi = {10.1007/s00429-018-1697-y},
url = {https://juser.fz-juelich.de/record/849856},
}