000849926 001__ 849926
000849926 005__ 20240619083547.0
000849926 037__ $$aFZJ-2018-04022
000849926 041__ $$aEnglish
000849926 1001_ $$0P:(DE-Juel1)131034$$aWiegand, Simone$$b0$$eCorresponding author
000849926 1112_ $$cUniversity Akron$$d2018-07-02 - 2018-07-02$$wUSA
000849926 245__ $$aThermophoresis and the ‚Origin-of-Life‘ concept$$f2018-07-02 - 
000849926 260__ $$c2018
000849926 3367_ $$033$$2EndNote$$aConference Paper
000849926 3367_ $$2DataCite$$aOther
000849926 3367_ $$2BibTeX$$aINPROCEEDINGS
000849926 3367_ $$2ORCID$$aLECTURE_SPEECH
000849926 3367_ $$0PUB:(DE-HGF)31$$2PUB:(DE-HGF)$$aTalk (non-conference)$$btalk$$mtalk$$s1544017229_14780$$xInvited
000849926 3367_ $$2DINI$$aOther
000849926 520__ $$aFormamide is of special interest in the 'origin-of-life' concept, because it was shown to form a number of prebiotic molecules under catalytic conditions and at sufficiently high concentrations [1]. For nucleotides and short DNA strands, numerical finite-element calculations have shown that a high degree of accumulation in hydrothermal pores occurs [2]. Using thermophoretic data of the formamide/water system measured with Infra-Red Thermal Diffusion Forced Rayleigh Scattering (IR-TDFRS) we show that the same combination of thermophoresis and convection in hydrothermal pores leads to accumulation of formamide up to concentrations high enough to initiate synthesis of prebiotic nucleobases. The high degree of formamide accumulation is due to an unusual temperature and concentration dependence of the thermophoretic behaviour of formamide. Starting with a formamide concentration of 10-3 wt%, estimated to be typical in shallow lakes on early earth, the accumulation-fold in part of the pores increases strongly with increasing aspect ratio of the pores, and saturates to highly concentrated aqueous formamide solutions of approximately 85 wt% at large aspect ratios [3].  Time dependent studies show that these high concentrations are reached after 45-90 days. Further, we derived a heuristic model to illuminate the accumulation process and understand the dependence of the accumulation on pore geometry 
000849926 536__ $$0G:(DE-HGF)POF3-551$$a551 - Functional Macromolecules and Complexes (POF3-551)$$cPOF3-551$$fPOF III$$x0
000849926 909CO $$ooai:juser.fz-juelich.de:849926$$pVDB
000849926 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131034$$aForschungszentrum Jülich$$b0$$kFZJ
000849926 9131_ $$0G:(DE-HGF)POF3-551$$1G:(DE-HGF)POF3-550$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lBioSoft – Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences$$vFunctional Macromolecules and Complexes$$x0
000849926 9141_ $$y2018
000849926 920__ $$lyes
000849926 9201_ $$0I:(DE-Juel1)ICS-3-20110106$$kICS-3$$lWeiche Materie $$x0
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000849926 980__ $$aI:(DE-Juel1)ICS-3-20110106
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