TY  - JOUR
AU  - Eickhoff, S. B.
AU  - Nickl-Jockschat, T.
AU  - Kurth, F.
TI  - Metaanalysen in der klinischen Hirnforschung
JO  - Der Nervenarzt
VL  - 81
SN  - 0028-2804
CY  - Berlin
PB  - Springer
M1  - PreJuSER-8508
SP  - 32-38
PY  - 2010
N1  - Record converted from VDB: 12.11.2012
AB  - Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) have brought about an immense increase in findings on the localization of motor, cognitive, and affective processes in the human brain. However, considerable discrepancy still exists between the multitude of available studies and the limited validity of the individual experiments. Quantitative, coordinate-based meta-analyses are suited to objectively integrate these numerous findings as completely as possible. There are a number of different methods for coordinate-based voxel-wise meta-analyses, but the technique of"activation likelihood estimation" (ALE) has largely prevailed. This contribution describes the principles, methods, and statistical analysis of ALE meta-analyses and their potential for basic research in neuroscience and clinical brain research.
KW  - Brain Mapping
KW  - Data Interpretation, Statistical
KW  - Evidence-Based Medicine
KW  - Humans
KW  - Magnetic Resonance Imaging
KW  - Meta-Analysis as Topic
KW  - Positron-Emission Tomography
KW  - Sensitivity and Specificity
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:20066395
UR  - <Go to ISI:>//WOS:000273808700005
DO  - DOI:10.1007/s00115-009-2826-x
UR  - https://juser.fz-juelich.de/record/8508
ER  -