% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Poeppl:850822,
      author       = {Poeppl, Timm B. and Donges, Maximilian R. and Mokros,
                      Andreas and Rupprecht, Rainer and Fox, Peter T. and Laird,
                      Angela R. and Bzdok, Danilo and Langguth, Berthold and
                      Eickhoff, Simon},
      title        = {{A} view behind the mask of sanity: meta-analysis of
                      aberrant brain activity in psychopaths},
      journal      = {Molecular psychiatry},
      volume       = {24},
      issn         = {1476-5578},
      address      = {London},
      publisher    = {Macmillan},
      reportid     = {FZJ-2018-04593},
      pages        = {463–470},
      year         = {2019},
      note         = {PTF is supported by the National Institute of Mental Health
                      (R01-MH074457). DB is funded by the Deutsche
                      Forschungsgemeinschaft (DFG, BZ2/2-1, BZ2/3-1, and BZ2/4-1;
                      International Research Training Group IRTG2150), Amazon AWS
                      Research Grant, the German National Academic Foundation, and
                      the START-Program of the Faculty of Medicine, RWTH Aachen.
                      SBE is supported by the Deutsche Forschungsgemeinschaft
                      (DFG, EI 816/4-1, EI 816/6-1), the National Institute of
                      Mental Health (R01-MH074457), the Helmholtz Portfolio Theme
                      “Supercomputing and Modeling for the Human Brain,” and
                      the European Union’ s Horizon 2020 Research and Innovation
                      Programme under Grant Agreement No. 7202070 (HBP
                      SGA1)Gebühren ergänzt am 04.10.18},
      abstract     = {Psychopathy is a disorder of high public concern because it
                      predicts violence and offense recidivism. Recent brain
                      imaging studies suggest abnormal brain activity underlying
                      psychopathic behavior. No reliable pattern of altered neural
                      activity has been disclosed so far. This study sought to
                      identify consistent changes of brain activity in psychopaths
                      and to investigate whether these could explain known
                      psychopathology. First, we used activation likelihood
                      estimation (p < 0.05, corrected) to meta-analyze brain
                      activation changes associated with psychopathy across 28
                      functional magnetic resonance imaging studies reporting 753
                      foci from 155 experiments. Second, we characterized the
                      ensuing regions functionally by employing metadata of a
                      large-scale neuroimaging database (p < 0.05, corrected).
                      Psychopathy was consistently associated with decreased brain
                      activity in the right laterobasal amygdala, the dorsomedial
                      prefrontal cortex, and bilaterally in the lateral prefrontal
                      cortex. A robust increase of activity was observed in the
                      fronto-insular cortex on both hemispheres. Data-driven
                      functional characterization revealed associations with
                      semantic language processing (left lateral prefrontal and
                      fronto-insular cortex), action execution and pain processing
                      (right lateral prefrontal and left fronto-insular), social
                      cognition (dorsomedial prefrontal cortex), and emotional as
                      well as cognitive reward processing (right amygdala and
                      fronto-insular cortex). Aberrant brain activity related to
                      psychopathy is located in prefrontal, insular, and limbic
                      regions. Physiological mental functions fulfilled by these
                      brain regions correspond to disturbed behavioral patterns
                      pathognomonic for psychopathy. Hence, aberrant brain
                      activity may not just be an epiphenomenon of psychopathy but
                      directly related to the psychopathology of this disorder.},
      cin          = {INM-7},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572) / HBP SGA1 -
                      Human Brain Project Specific Grant Agreement 1 (720270)},
      pid          = {G:(DE-HGF)POF3-572 / G:(EU-Grant)720270},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30038232},
      UT           = {WOS:000459254400013},
      doi          = {10.1038/s41380-018-0122-5},
      url          = {https://juser.fz-juelich.de/record/850822},
}