% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Strehlau:851126,
      author       = {Strehlau, Jenny and Weber, Till and Lürenbaum, Constantin
                      and Bornhorst, Julia and Galla, Hans-Joachim and Schwerdtle,
                      Tanja and Winter, Martin and Nowak, Sascha},
      title        = {{T}owards quantification of toxicity of lithium ion battery
                      electrolytes - development and validation of a liquid-liquid
                      extraction {GC}-{MS} method for the determination of organic
                      carbonates in cell culture materials},
      journal      = {Analytical and bioanalytical chemistry},
      volume       = {409},
      number       = {26},
      issn         = {0016-1152},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {FZJ-2018-04828},
      pages        = {6123 - 6131},
      year         = {2017},
      abstract     = {A novel method based on liquid-liquid extraction with
                      subsequent gas chromatography separation and mass
                      spectrometric detection (GC-MS) for the quantification of
                      organic carbonates in cell culture materials is presented.
                      Method parameters including the choice of extraction
                      solvent, of extraction method and of extraction time were
                      optimised and the method was validated. The setup allowed
                      for determination within a linear range of more than two
                      orders of magnitude. The limits of detection (LODs) were
                      between 0.0002 and 0.002 mmol/L and the repeatability
                      precisions were in the range of $1.5–12.9\%.$ It could be
                      shown that no matrix effects were present and recovery rates
                      between 98 and $104\%$ were achieved. The methodology was
                      applied to cell culture models incubated with commercial
                      lithium ion battery (LIB) electrolytes to gain more insight
                      into the potential toxic effects of these compounds. The
                      stability of the organic carbonates in cell culture medium
                      after incubation was studied. In a porcine model of the
                      blood-cerebrospinal fluid (CSF) barrier, it could be shown
                      that a transfer of organic carbonates into the brain facing
                      compartment took place.},
      cin          = {IEK-12},
      ddc          = {540},
      cid          = {I:(DE-Juel1)IEK-12-20141217},
      pnm          = {131 - Electrochemical Storage (POF3-131)},
      pid          = {G:(DE-HGF)POF3-131},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28776071},
      UT           = {WOS:000411709000008},
      doi          = {10.1007/s00216-017-0549-6},
      url          = {https://juser.fz-juelich.de/record/851126},
}