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@ARTICLE{Papagiannopoulos:851480,
author = {Papagiannopoulos, Aristeidis and Vlassi, Eleni and Pispas,
Stergios and Houston, Judith},
title = {{A}ssociation and {I}nternal {M}orphology of
{S}elf-{A}ssembled {HPP}h{O}x/{BSA} {H}ybrid {N}anoparticles
in {A}queous {S}olutions},
journal = {The journal of physical chemistry / B},
volume = {122},
number = {29},
issn = {1520-5207},
address = {Washington, DC},
publisher = {Soc.},
reportid = {FZJ-2018-05116},
pages = {7426 - 7435},
year = {2018},
abstract = {We investigate the formation of hybrid
polyelectrolyte/protein nanoparticles by associations
between aggregates of partially hydrolyzed
poly(2-phenyl-2-oxazoline) (HPPhOx) and bovine serum albumin
(BSA) in aqueous solutions. Light scattering experiments
show that at conditions of low salt, BSA creates
interaggregate bridges and increases the size of the HPPhOx
nanoparticles. At high salt contents, breaking of aggregates
leads to well-defined nanoparticles. The interior of the
formed nanoparticles is probed by small-angle neutron
scattering. At low salt, diffuse arrangements are observed,
whereas at high salt concentration, scattering is dominated
by well-defined hydrophobic domains enhanced by the
incorporation of BSA. This system shows that the combination
of hydrophobic and electrostatic interactions in
random-amphiphilic-polyelectrolyte/protein complexes can be
used to determine the properties of self-assembled hybrid
multifunctional nanoparticles.},
cin = {JCNS (München) ; Jülich Centre for Neutron Science JCNS
(München) ; JCNS-FRM-II / Neutronenstreuung ; JCNS-1},
ddc = {530},
cid = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
I:(DE-Juel1)JCNS-1-20110106},
pnm = {6G15 - FRM II / MLZ (POF3-6G15) / 6G4 - Jülich Centre for
Neutron Research (JCNS) (POF3-623)},
pid = {G:(DE-HGF)POF3-6G15 / G:(DE-HGF)POF3-6G4},
experiment = {EXP:(DE-MLZ)KWS2-20140101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29947516},
UT = {WOS:000440519900023},
doi = {10.1021/acs.jpcb.8b04364},
url = {https://juser.fz-juelich.de/record/851480},
}