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@ARTICLE{Creyaufmller:852422,
author = {Creyaufmüller, M. and Heim, Stefan and Habel, Ute and
Mühlhaus, J.},
title = {{T}he influence of semantic associations on sentence
production in schizophrenia: {A}n f{MRI} study},
journal = {European archives of psychiatry and clinical neuroscience},
volume = {270},
issn = {0003-9373},
address = {Darmstadt},
publisher = {Steinkopff},
reportid = {FZJ-2018-05376},
pages = {359–372},
year = {2020},
abstract = {One of the most prominent symptoms of schizophrenia is
thought disorder, which manifests itself in language
production difficulties. In patients with thought disorders
the associations are loosened and sentence production is
impaired. The determining behavioral and neural mechanisms
of sentence production are still an important subject of
recent research and have not yet been fully understood. The
aim of the current study was to examine the influence of
associative relations and distractor modalities on sentence
production in healthy participants and participants with
schizophrenia. Therefore, reaction times and neural
activation of 12 healthy subjects and 13 subjects with
schizophrenia were compared in an adapted picture word
interference paradigm (PWI). No significant group
differences were found, neither on the behavioral nor on the
neural level. On the behavioral level, for the entire group
incremental sentence processing was found, i.e. processing
of the second noun only starts after the first noun was
processed. At the neural level, activation was discovered in
the bilateral caudate nuclei and the cerebellum. Those
activations could be related to response enhancement and
suppression as well as to the modulation of cognitive
processes.},
cin = {INM-1 / INM-10},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-10-20170113},
pnm = {571 - Connectivity and Activity (POF3-571)},
pid = {G:(DE-HGF)POF3-571},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30094543},
UT = {WOS:000519441200009},
doi = {10.1007/s00406-018-0936-9},
url = {https://juser.fz-juelich.de/record/852422},
}