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@ARTICLE{Eickhoff:852601,
author = {Eickhoff, Roman and Eickhoff, Simon and Katurman, Serdar
and Klink, Christian D. and Heise, Daniel and Kroh, Andreas
and Neumann, Ulf P. and Binnebösel, Marcel},
title = {{I}nfluence of suture technique on anastomotic leakage
rate—a retrospective analyses comparing
interrupted—versus continuous—sutures},
journal = {International journal of colorectal disease},
volume = {34},
number = {1},
issn = {0179-1958},
address = {Berlin},
publisher = {Springer},
reportid = {FZJ-2018-05505},
pages = {55-61},
year = {2019},
abstract = {Purpose While many hospitals consider a continuous sutured
colonic anastomosis with monofilamental fiber the current
state ofthe art, others have advocated for interrupted
sutures as the gold standard. The aim of the study was to
evaluate the influence ofsuture technique on leakage rate
(primary endpoint), wound infections, postoperative stay,
and mortality.Methods Retrospective analyses of 347 patients
(273 elective, 74 urgent) over 6 years with a handsewn
colonic anastomosis (190interrupted, 157 continuous),
excluding sigma and rectum anastomosis. Demographic and
surgical baseline characteristics wereused as competing
predictors.Results Overall leakage rate was $9\%$ but
strongly dependent on suture technique (interrupted: $16\%;$
continuous: $2.5\%;$ p = 0.001)yielding an odds ratio of
5.10 $[95\%$ CI: 2.55, 6.71] (relative risk of leakage). No
other variable showed a significant influence onleakage
rate. Postoperative stay was prolonged in the interrupted
suture group (23 ± 15 vs. 16 ± 11 days; p = 0.000,
attributableeffect 7.5 days [4.7, 10.3]).Conclusions Our
results indicate a highly significant reduction of
anastomotic leakage rate and postoperative stay that
generalizeto the underlying population by continuous sutures
in handsewn colonic anastomosis. In the absence of
randomized prospectivestudies, the current results provide
the yet strongest evidence for the superiority of continuous
sutures.Keywords Anastomotic leakage . Interrupted suture
technique . Continuous suture technique . Anastomotic
technique . Colonanastomosis},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30250969},
UT = {WOS:000455688100006},
doi = {10.1007/s00384-018-3168-6},
url = {https://juser.fz-juelich.de/record/852601},
}