TY  - JOUR
AU  - Liu, Yang
AU  - Kurtán, Tibor
AU  - Mándi, Attila
AU  - Weber, Horst
AU  - Wang, Changyun
AU  - Hartmann, Rudolf
AU  - Lin, Wenhan
AU  - Daletos, Georgios
AU  - Proksch, Peter
TI  - A novel 10-membered macrocyclic lactone from the mangrove-derived endophytic fungus Annulohypoxylon sp.
JO  - Tetrahedron letters
VL  - 59
IS  - 7
SN  - 0040-4039
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - FZJ-2018-07357
SP  - 632 - 636
PY  - 2018
AB  - A novel 10-membered macrolactone, hypoxylide (1), was isolated from the endophytic fungus Annulohypoxylon sp. that was obtained from the Mangrove plant Rhizophora racemosa. The structure and absolute configuration of 1 were unambiguously elucidated by comprehensive 1D and 2D NMR, as well as by HRESIMS and ECD spectroscopic analyses. Hypoxylide (1) features an unprecedented polyketide skeleton comprised of a trihydroxynaphthalene-dione moiety fused to a decalactone ring. A plausible biosynthetic pathway of this novel metabolite is proposed.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000424717600012
DO  - DOI:10.1016/j.tetlet.2018.01.001
UR  - https://juser.fz-juelich.de/record/858485
ER  -