%0 Journal Article
%A Grasmik, Viktoria
%A Breisch, Marina
%A Loza, Kateryna
%A Heggen, Marc
%A Köller, Manfred
%A Sengstock, Christina
%A Epple, Matthias
%T Synthesis and biological characterization of alloyed silver–platinum nanoparticles: from compact core–shell nanoparticles to hollow nanoalloys
%J RSC Advances
%V 8
%N 67
%@ 2046-2069
%C London
%I RSC Publishing
%M FZJ-2018-07467
%P 38582 - 38590
%D 2018
%X Bimetallic nanoparticles consisting of silver and platinum were prepared by a modified seeded-growth process in water in the full composition range in steps of 10 mol%. The particles had diameters between 15–25 nm as determined by disc centrifugal sedimentation (DCS) and transmission electron microscopy (TEM). Whereas particles with high platinum content were mostly spherical with a solid silver core/platinum shell structure, mostly hollow alloyed nanoparticles were observed with increasing silver content. The internal structure and the elemental distribution within the particles were elucidated by high-resolution transmission electron microscopy (HRTEM) in combination with energy-dispersive X-ray spectroscopy (EDX). The particles were cytotoxic for human mesenchymal stem cells (hMSC) above 50 mol% silver. This was explained by dissolution experiments where silver was only released at and above 50 mol% silver. In contrast, platinum-rich particles (less than 50 mol% silver) did not release any silver ions. This indicates that the presence of platinum inhibits the oxidative dissolution of silver.
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000451075500051
%R 10.1039/C8RA06461J
%U https://juser.fz-juelich.de/record/858607