TY  - JOUR
AU  - Grasmik, Viktoria
AU  - Breisch, Marina
AU  - Loza, Kateryna
AU  - Heggen, Marc
AU  - Köller, Manfred
AU  - Sengstock, Christina
AU  - Epple, Matthias
TI  - Synthesis and biological characterization of alloyed silver–platinum nanoparticles: from compact core–shell nanoparticles to hollow nanoalloys
JO  - RSC Advances
VL  - 8
IS  - 67
SN  - 2046-2069
CY  - London
PB  - RSC Publishing
M1  - FZJ-2018-07467
SP  - 38582 - 38590
PY  - 2018
AB  - Bimetallic nanoparticles consisting of silver and platinum were prepared by a modified seeded-growth process in water in the full composition range in steps of 10 mol%. The particles had diameters between 15–25 nm as determined by disc centrifugal sedimentation (DCS) and transmission electron microscopy (TEM). Whereas particles with high platinum content were mostly spherical with a solid silver core/platinum shell structure, mostly hollow alloyed nanoparticles were observed with increasing silver content. The internal structure and the elemental distribution within the particles were elucidated by high-resolution transmission electron microscopy (HRTEM) in combination with energy-dispersive X-ray spectroscopy (EDX). The particles were cytotoxic for human mesenchymal stem cells (hMSC) above 50 mol% silver. This was explained by dissolution experiments where silver was only released at and above 50 mol% silver. In contrast, platinum-rich particles (less than 50 mol% silver) did not release any silver ions. This indicates that the presence of platinum inhibits the oxidative dissolution of silver.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000451075500051
DO  - DOI:10.1039/C8RA06461J
UR  - https://juser.fz-juelich.de/record/858607
ER  -