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000858929 1001_ $$0P:(DE-Juel1)164254$$aLerche, Christoph$$b0$$eCorresponding author
000858929 245__ $$aCHAPTER 10. MR-PET Instrumentation
000858929 260__ $$aCambridge$$bRoyal Society of Chemistry$$c2018
000858929 29510 $$aHybrid MR-PET Imaging / Shah, N Jon (Editor)   
000858929 300__ $$a214 - 228
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000858929 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$bcontb$$mcontb$$s1553865083_23697
000858929 4900_ $$aNew Developments in NMR
000858929 520__ $$aThe combination of several imaging modalities into a hybrid device has enabled a straightforward and accurate solution for the investigation of multiparametric processes in vivo. All existing imaging modalities have both strengths and weaknesses. For instance, computed tomography (CT) is an excellent modality for imaging bones. Magnetic resonance tomography images the effects of a manifold of interaction mechanisms between the spin ensemble and/with its environment and other nuclei. The differences in these interactions depend much more on the tissue type, its microscopic environment and interactions at the quantum level and therefore MR images provide a wide variety of superior soft tissue contrasts. Gamma scintigraphy, single photon emission computed tomography and positron emission tomography detect single radioactive decays from tagged molecules and can infer the spatial position of the decays from a few thousand decays. Thus, the sensitivity of these modalities is very high, but the spatial resolution is very low. Instead of pushing CT and MRI technology towards molecular imaging and positron emission tomography (PET) technology towards structural imaging, a much more promising approach is to further optimise the strengths of these modalities by combining them into hybrid devices. The combination of MRI and PET has been the second bi-modality, which resulted in commercially available hybrid scanners for animal and human imaging. In this chapter, the most important mutual interferences of PET and MRI, together with technical solutions for minimising them, are presented and discussed.
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000858929 7001_ $$0P:(DE-Juel1)131761$$aFelder, J.$$b1
000858929 7001_ $$0P:(DE-Juel1)164356$$aChoi, C.-H.$$b2
000858929 773__ $$a10.1039/9781788013062-00214
000858929 7870_ $$0FZJ-2018-02194$$aShah, N. J.$$dCambridge : Royal Society of Chemistry, 2018$$iRelatedTo$$r$$tHybrid MR-PET Imaging: Systems, Methods and Applications
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000858929 9141_ $$y2019
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