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@INBOOK{Lerche:858929,
      author       = {Lerche, Christoph and Felder, J. and Choi, C.-H.},
      title        = {{CHAPTER} 10. {MR}-{PET} {I}nstrumentation},
      address      = {Cambridge},
      publisher    = {Royal Society of Chemistry},
      reportid     = {FZJ-2018-07765},
      series       = {New Developments in NMR},
      pages        = {214 - 228},
      year         = {2018},
      comment      = {Hybrid MR-PET Imaging / Shah, N Jon (Editor)},
      booktitle     = {Hybrid MR-PET Imaging / Shah, N Jon
                       (Editor)},
      abstract     = {The combination of several imaging modalities into a hybrid
                      device has enabled a straightforward and accurate solution
                      for the investigation of multiparametric processes in vivo.
                      All existing imaging modalities have both strengths and
                      weaknesses. For instance, computed tomography (CT) is an
                      excellent modality for imaging bones. Magnetic resonance
                      tomography images the effects of a manifold of interaction
                      mechanisms between the spin ensemble and/with its
                      environment and other nuclei. The differences in these
                      interactions depend much more on the tissue type, its
                      microscopic environment and interactions at the quantum
                      level and therefore MR images provide a wide variety of
                      superior soft tissue contrasts. Gamma scintigraphy, single
                      photon emission computed tomography and positron emission
                      tomography detect single radioactive decays from tagged
                      molecules and can infer the spatial position of the decays
                      from a few thousand decays. Thus, the sensitivity of these
                      modalities is very high, but the spatial resolution is very
                      low. Instead of pushing CT and MRI technology towards
                      molecular imaging and positron emission tomography (PET)
                      technology towards structural imaging, a much more promising
                      approach is to further optimise the strengths of these
                      modalities by combining them into hybrid devices. The
                      combination of MRI and PET has been the second bi-modality,
                      which resulted in commercially available hybrid scanners for
                      animal and human imaging. In this chapter, the most
                      important mutual interferences of PET and MRI, together with
                      technical solutions for minimising them, are presented and
                      discussed.},
      cin          = {INM-4 / INM-11 / JARA-BRAIN},
      cid          = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)7},
      doi          = {10.1039/9781788013062-00214},
      url          = {https://juser.fz-juelich.de/record/858929},
}