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@INBOOK{Caldeira:858930,
author = {Caldeira, L. and Kops, E. Rota and da Silva, N. A. and
Herzog, H.},
title = {{CHAPTER} 11. {MR}-based {C}orrections for {Q}uantitative
{PET} {I}mage},
address = {Cambridge},
publisher = {Royal Society of Chemistry},
reportid = {FZJ-2018-07766},
series = {New Developments in NMR},
pages = {229 - 258},
year = {2018},
comment = {Hybrid MR-PET Imaging / Shah, N Jon (Editor)},
booktitle = {Hybrid MR-PET Imaging / Shah, N Jon
(Editor)},
abstract = {In this chapter, we address the correction of positron
emission tomography (PET) images using magnetic resonance
(MR) information, namely attenuation correction (AC),
partial volume correction (PVC) and the arterial input
function (AIF). The use of quantitative brain PET imaging is
a basic prerequisite in research as well as in the clinical
PET environment. Consequently, a reliable attenuation
correction method for the PET data is imperative. Here, we
describe the attenuation process and provide an outline of
several attenuation correction methods, all based on
simultaneously acquired MR sequences. When absolute
quantification of, e.g., blood flow and metabolism in small
anatomical structures is required, the spatial resolution of
PET scanners can be a limiting factor. The partial volume
effect resulting from the limited spatial resolution is
explained and correction methods are presented in this
chapter. When the visualisation of kinetic processes, such
as cerebral glucose consumption or cerebral blood flow, is
required, fully quantitative data can only be acquired with
knowledge of the arterial input function. This information
can be obtained using MR images, which make it possible to
extract exactly the information required. The ways to obtain
such a function, the methods to use it and the related
uncertainties are also discussed in this chapter.},
cin = {INM-4 / INM-11 / JARA-BRAIN},
cid = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
$I:(DE-82)080010_20140620$},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)7},
doi = {10.1039/9781788013062-00229},
url = {https://juser.fz-juelich.de/record/858930},
}