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@INBOOK{Willuweit:858935,
author = {Willuweit, A. and Lohmann, P. and Stegmayr, C.},
title = {{CHAPTER} 19. {P}reclinical {A}pplications of {MR}-{PET}},
address = {Cambridge},
publisher = {Royal Society of Chemistry},
reportid = {FZJ-2018-07771},
series = {New Developments in NMR},
pages = {368 - 378},
year = {2018},
comment = {Hybrid MR-PET Imaging / Shah, N Jon (Editor)
doi:10.1039/9781788013062},
booktitle = {Hybrid MR-PET Imaging / Shah, N Jon
(Editor) doi:10.1039/9781788013062},
abstract = {Combined magnetic resonance-positron emission tomography
(MR-PET), acquired either simultaneously in hybrid scanners
or sequentially with standalone machines, offers various
applications for preclinical studies. For example, in order
to develop new diagnostic tools for translation into the
clinic, proof-of-concept studies enable the development and
implementation of new hardware components and MRI sequences.
New PET tracers and contrast agents can also be applied and
cross-validated with either modality. Currently, dual-probes
are under development, which synergistically combine the
advantages of imaging agents from PET and magnetic resonance
imaging. MR-PET is also being implemented more frequently to
support the monitoring of preclinical treatment studies for
the development of new therapeutic agents and strategies.
Further applications of combined MR-PET are multi-modal
validation studies of new animal models and analysis of
brain function and disease mechanisms, which can be
monitored longitudinally.},
cin = {INM-4 / INM-11 / JARA-BRAIN},
cid = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
$I:(DE-82)080010_20140620$},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)7},
doi = {10.1039/9781788013062-00368},
url = {https://juser.fz-juelich.de/record/858935},
}