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@ARTICLE{Pallast:859032,
author = {Pallast, N. and Wieters, F. and Nill, M. and Fink, G. R.
and Aswendt, M.},
title = {{C}loud-based relational database for multimodal animal
data},
journal = {Database},
volume = {2018},
issn = {1758-0463},
address = {Oxford},
publisher = {Oxford University Press},
reportid = {FZJ-2019-00002},
pages = {bay124},
year = {2018},
abstract = {Pre-clinical research builds on a large variety of in vivo
and ex vivo tools such as non-invasive imaging, microscopy,
and analysis of gene expression. To work efficiently with
multimodal data and correlate results across scales, it is
of particular importance to have easy access to all data
points from different specimen, e.g. the magnetic resonance
imaging (MRI) data from different time points, and the
post-mortem histology. That requires an efficient data
management, which is customizable and designed to relate all
applied methods, raw data and analyses to one specific
animal. Despite increasing demands to handle such complex
data, most pre-clinical labs have not yet established such
an electronic database. Here, we present a novel cloud-based
relational database for multimodal animal data, which
operates on commercial software. We have implemented data
fields for various pre-clinical features such as MRI,
histology and behaviour. Automated procedures replace manual
and recurrent calculations. Pre-set plotting and printing
features provide efficient analysis and documentation. The
database template is useful for all labs working with
laboratory animals and the adaption to specific research
projects requires no prior scripting expertise. The database
works operating-system independent through the web browser
and allows multiple users to work simultaneously. The data
entry is monitored and restricted for particular tests
according to the user management in order to keep for
example users during the experiment blinded for the
experimental group. The database improves data
accessibility, standardization of data recording and data
handling efficiency in pre-clinical research.},
cin = {INM-3},
ddc = {570},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30576483},
UT = {WOS:000453806800003},
doi = {10.1093/database/bay124},
url = {https://juser.fz-juelich.de/record/859032},
}