% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Kalbe:859036,
      author       = {Kalbe, Elke and Roheger, Mandy and Paluszak, Kay and Meyer,
                      Julia and Becker, Jutta and Fink, Gereon R. and Kukolja,
                      Juraj and Rahn, Andreas and Szabados, Florian and Wirth,
                      Brunhilde and Kessler, Josef},
      title        = {{E}ffects of a {C}ognitive {T}raining {W}ith and {W}ithout
                      {A}dditional {P}hysical {A}ctivity in {H}ealthy {O}lder
                      {A}dults: {A} {F}ollow-{U}p 1 {Y}ear {A}fter a {R}andomized
                      {C}ontrolled {T}rial},
      journal      = {Frontiers in aging neuroscience},
      volume       = {10},
      issn         = {1663-4365},
      address      = {Lausanne},
      publisher    = {Frontiers Research Foundation},
      reportid     = {FZJ-2019-00006},
      pages        = {407},
      year         = {2018},
      abstract     = {Background: Combining cognitive training (CT) with physical
                      activity (CPT) has been suggested to be most effective in
                      maintaining cognition in healthy older adults, but data are
                      scarce and inconsistent regarding long-term effects
                      (follow-up; FU) and predictors of success.Objective: To
                      investigate the 1-year FU effects of CPT versus CT and CPT
                      plus counseling (CPT+C), and to identify predictors for CPT
                      success at FU.Setting and Participants: We included 55
                      healthy older participants in the data analyses; 18
                      participants (CPT group) were used for the predictor
                      analysis.Interventions: In a randomized controlled trial,
                      participants conducted a CT, CPT, or CPT+C for 7
                      weeks.Outcome Measures: Overall cognition, verbal, figural,
                      and working memory, verbal fluency, attention, planning, and
                      visuo-construction.Results: While within-group comparisons
                      showed cognitive improvements for all types of training,
                      only one significant interaction Group × Time favoring CPT
                      in comparison to CPT+C was found for overall cognition and
                      verbal long-term memory. The most consistent predictor for
                      CPT success (in verbal short-term memory, verbal fluency,
                      attention) was an initial low baseline performance. Lower
                      education predicted working memory gains. Higher levels of
                      insulin-like growth factor 1 (IGF-1) and lower levels of
                      brain-derived neurotrophic factor at baseline (BDNF)
                      predicted alternating letter verbal fluency
                      gains.Discussion: Within-group comparisons indicate that all
                      used training types are helpful to maintain cognition. The
                      fact that cognitive and sociodemographic data as well as
                      nerve growth factors predict long-term benefits of CPT
                      contributes to the understanding of the mechanisms
                      underlying training success and may ultimately help to adapt
                      training to individual profiles},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000453665900001},
      doi          = {10.3389/fnagi.2018.00407},
      url          = {https://juser.fz-juelich.de/record/859036},
}