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@ARTICLE{Naumova:859138,
      author       = {Naumova, Natalia and Hlukhova, Hanna and Barannik,
                      Alexander and Gubin, Alexey and Protsenko, Irina and
                      Cherpak, Nickolay and Vitusevich, Svetlana},
      title        = {{M}icrowave characterization of low-molecular-weight
                      antioxidant specific biomarkers},
      journal      = {Biochimica et biophysica acta / General subjects General
                      subjects [...]},
      volume       = {1863},
      number       = {1},
      issn         = {0304-4165},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {FZJ-2019-00074},
      pages        = {226 - 231},
      year         = {2019},
      abstract     = {Antioxidants play a crucial role in the life sciences, as
                      the regulators of biochemical reactions. We studied the
                      dielectric properties of the low-molecular weight
                      antioxidant specific biomarkers sodium ascorbate and
                      glutathione in solutions of different concentrations. The
                      biomarkers are multifunctional metabolites relevant to the
                      reactive oxygen species (ROS) scavenging system of cells.
                      The newly developed high-Q microwave whispering-gallery-mode
                      (WGM) dielectric resonator based technique was applied. The
                      technique allows investigation of liquids of nanoliter
                      volumes filled in microfluidic channel within several
                      milliseconds. The revealed peculiarities in the dependence
                      of permittivity on concentrations of the sodium ascorbate
                      and glutathione solutions are explained by differences in
                      relaxation times and loses introduced by molecules of
                      different shapes. We suggest that this novel approach offers
                      the potential for the detection and characterization of
                      ROS-relevant biomarkers with millisecond-time resolution.},
      cin          = {ICS-8},
      ddc          = {610},
      cid          = {I:(DE-Juel1)ICS-8-20110106},
      pnm          = {523 - Controlling Configuration-Based Phenomena (POF3-523)},
      pid          = {G:(DE-HGF)POF3-523},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30342155},
      UT           = {WOS:000452343100021},
      doi          = {10.1016/j.bbagen.2018.10.013},
      url          = {https://juser.fz-juelich.de/record/859138},
}