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@ARTICLE{Risius:859215,
author = {Risius, Okka and Onur, Oezguer A. and Dronse, Julian and
von Reutern, Boris and Richter, Nils and Fink, Gereon R. and
Kukolja, Juraj},
title = {{N}eural {N}etwork {C}onnectivity {D}uring {P}ost-encoding
{R}est: {L}inking {E}pisodic {M}emory {E}ncoding and
{R}etrieval},
journal = {Frontiers in human neuroscience},
volume = {12},
issn = {1662-5161},
address = {Lausanne},
publisher = {Frontiers Research Foundation},
reportid = {FZJ-2019-00096},
pages = {528},
year = {2019},
abstract = {Commonly, a switch between networks mediating memory
encoding and those mediating retrieval is observed. This may
not only be due to differential involvement of neural
resources due to distinct cognitive processes but could also
reflect the formation of new memory traces and their dynamic
change during consolidation. We used resting state fMRI to
measure functional connectivity (FC) changes during
post-encoding rest, hypothesizing that during this phase,
new functional connections between encoding- and
retrieval-related regions are created. Interfering and
reminding tasks served as experimental modulators to
corroborate that the observed FC differences indeed reflect
changes specific to post-encoding rest. The right inferior
occipital and fusiform gyri (active during encoding) showed
increased FC with the left inferior frontal gyrus and the
left middle temporal gyrus (MTG) during post-encoding rest.
Importantly, the left MTG subsequently also mediated
successful retrieval. This finding might reflect the
formation of functional connections between encoding- and
retrieval-related regions during undisturbed post-encoding
rest. These connections were vulnerable to experimental
modulation: Cognitive interference disrupted FC changes
during post-encoding rest resulting in poorer memory
performance. The presentation of reminders also inhibited FC
increases but without affecting memory performance. Our
results contribute to a better understanding of the
mechanisms by which post-encoding rest bridges the gap
between encoding- and retrieval-related networks.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30687046},
UT = {WOS:000455342300001},
doi = {10.3389/fnhum.2018.00528},
url = {https://juser.fz-juelich.de/record/859215},
}