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@ARTICLE{Moussa:859436,
      author       = {Moussa, Mariam and Ebrahim, Weaam and Bonus, Michele and
                      Gohlke, Holger and Mándi, Attila and Kurtán, Tibor and
                      Hartmann, Rudolf and Kalscheuer, Rainer and Lin, Wenhan and
                      Liu, Zhen and Proksch, Peter},
      title        = {{C}o-culture of the fungus {F}usarium tricinctum with
                      {S}treptomyces lividans induces production of cryptic
                      naphthoquinone dimers},
      journal      = {RSC Advances},
      volume       = {9},
      number       = {3},
      issn         = {2046-2069},
      address      = {London},
      publisher    = {RSC Publishing},
      reportid     = {FZJ-2019-00292},
      pages        = {1491 - 1500},
      year         = {2019},
      abstract     = {Co-cultivation of the endophytic fungus Fusarium tricinctum
                      with Streptomyces lividans on solid rice medium led to the
                      production of four new naphthoquinone dimers, fusatricinones
                      A–D (1–4), and a new lateropyrone derivative,
                      dihydrolateropyrone (5), that were not detected in axenic
                      fungal controls. In addition, four known cryptic compounds,
                      zearalenone (7), (−)-citreoisocoumarin (8), macrocarpon C
                      (9) and 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (10),
                      that were likewise undetectable in extracts from fungal
                      controls, were obtained from the co-culture extracts. The
                      known antibiotically active compound lateropyrone (6), the
                      depsipeptides enniatins B (11), B1 (12) and A1 (13), and the
                      lipopeptide fusaristatin A (14), that were present in axenic
                      fungal controls and in co-culture extracts, were upregulated
                      in the latter. The structures of the new compounds were
                      elucidated by 1D and 2D NMR spectra as well as by HRESIMS
                      data. The relative and absolute configuration of
                      dihydrolateropyrone (5) was elucidated by TDDFT-ECD
                      calculations.},
      cin          = {JSC / NIC / ICS-6},
      ddc          = {540},
      cid          = {I:(DE-Juel1)JSC-20090406 / I:(DE-Juel1)NIC-20090406 /
                      I:(DE-Juel1)ICS-6-20110106},
      pnm          = {333 - Anti-infectives (POF3-333) / 511 - Computational
                      Science and Mathematical Methods (POF3-511) / Forschergruppe
                      Gohlke $(hkf7_20170501)$},
      pid          = {G:(DE-HGF)POF3-333 / G:(DE-HGF)POF3-511 /
                      $G:(DE-Juel1)hkf7_20170501$},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000457292800036},
      doi          = {10.1039/C8RA09067J},
      url          = {https://juser.fz-juelich.de/record/859436},
}