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@ARTICLE{Schlenk:859967,
      author       = {Schlenk, Mathias and Drechsler, Markus and Karg, Matthias
                      and Zimmermann, Walter and Trebbin, Martin and Förster,
                      Stephan},
      title        = {{S}plitting and separation of colloidal streams in
                      sinusoidal microchannels},
      journal      = {Lab on a chip},
      volume       = {18},
      number       = {20},
      issn         = {1473-0189},
      address      = {Cambridge},
      publisher    = {RSC},
      reportid     = {FZJ-2019-00773},
      pages        = {3163 - 3171},
      year         = {2018},
      abstract     = {The control of the distribution of colloidal particles in
                      microfluidic flows plays an important role in biomedical and
                      industrial applications. A particular challenge is to induce
                      cross-streamline migration in laminar flows, enabling the
                      separation of colloidal particles according to their size,
                      shape or elasticity. Here we show that viscoelastic fluids
                      can mediate cross-streamline migration of deformable
                      spherical and cylindrical colloidal particles in sinusoidal
                      microchannels at low Reynolds numbers. For colloidal streams
                      focused into the center of the channel entrance this leads
                      to a symmetric stream-splitting and separation into four
                      substreams. The degree of stream splitting and separation
                      can be controlled via the flow rates, viscoelasticity of the
                      focusing fluid, and the spatial microchannel modulation with
                      an upper limit when reaching the microchannel walls. We
                      demonstrate that this effect can be used to separate
                      flexible particles of different size and shape. This
                      methodology of cross-stream migration has thus great
                      potential for the passive separation of colloids and cells
                      in microfluidic channels.},
      cin          = {ICS-1 / Neutronenstreuung ; JCNS-1},
      ddc          = {540},
      cid          = {I:(DE-Juel1)ICS-1-20110106 / I:(DE-Juel1)JCNS-1-20110106},
      pnm          = {551 - Functional Macromolecules and Complexes (POF3-551) /
                      6G4 - Jülich Centre for Neutron Research (JCNS) (POF3-623)
                      / 6215 - Soft Matter, Health and Life Sciences (POF3-621)},
      pid          = {G:(DE-HGF)POF3-551 / G:(DE-HGF)POF3-6G4 /
                      G:(DE-HGF)POF3-6215},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30187066},
      UT           = {WOS:000448341000011},
      doi          = {10.1039/C8LC00255J},
      url          = {https://juser.fz-juelich.de/record/859967},
}