TY  - JOUR
AU  - Lohmann, Philipp
AU  - Werner, Jan-Michael
AU  - Shah, N.
AU  - Fink, Gereon Rudolf
AU  - Langen, Karl-Josef
AU  - Galldiks, Norbert
TI  - Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients
JO  - Cancers
VL  - 11
IS  - 2
SN  - 2072-6694
CY  - Basel
PB  - MDPI
M1  - FZJ-2019-01196
SP  - 153 -
PY  - 2019
AB  - Imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI) provide valuable information about brain tumor patients. Particularly amino acid PET, advanced MRI techniques, and combinations thereof are of great interest for the non-invasive assessment of biological characteristics in patients with primary or secondary brain cancer. A methodological innovation that potentially advances research in patients with brain tumors is the increasing availability of hybrid PET/MRI systems, which enables the simultaneous acquisition of both imaging modalities. Furthermore, the advent of ultra-high field MRI scanners operating at magnetic field strengths of 7 T or more will allow further development of metabolic MR imaging at higher resolution. This review focuses on the combination of amino acid PET with MR spectroscopic imaging, perfusion- and diffusion-weighted imaging, as well as chemical exchange saturation transfer in patients with high-grade gliomas, especially glioblastomas
LB  - PUB:(DE-HGF)16
C6  - pmid:30699942
UR  - <Go to ISI:>//WOS:000460747200027
DO  - DOI:10.3390/cancers11020153
UR  - https://juser.fz-juelich.de/record/860442
ER  -