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@ARTICLE{Samea:861112,
      author       = {Samea, Fateme and Soluki, Solmaz and Nejati, Vahid and
                      Zarei, Mojtaba and Cortese, Samuele and Eickhoff, Simon and
                      Tahmasian, Masoud and Eickhoff, Claudia},
      title        = {{B}rain alterations in children/adolescents with {ADHD}
                      revisited: a neuroimaging meta-analysis of 96 structural and
                      functional studies},
      journal      = {Neuroscience $\&$ biobehavioral reviews},
      volume       = {100},
      issn         = {0149-7634},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2019-01677},
      pages        = {1-8},
      year         = {2019},
      abstract     = {The findings of neuroimaging studies in
                      children/adolescents with ADHD, and even those of previous
                      meta-analyses, are divergent. Here, Activation Likelihood
                      Estimation meta-analysis, following the current
                      best-practice guidelines, was conducted. We searched
                      multiple databases and traced the references up to June
                      2018. Then, we extracted the reported coordinates reflecting
                      group comparison between ADHD and healthy subjects from 96
                      eligible studies, containing 1914 unique participants. The
                      analysis of pooled structural and functional, sub-analyses
                      restricted to modality, and in-/decreased contrast did not
                      yield any significant findings. However, further
                      sub-analyses in the task-fMRI experiments (neutral stimuli
                      only) led to aberrant activity in the left pallidum/putamen
                      and decreased activity (male subjects only) in the left
                      inferior frontal gyrus. The overall findings indicate a lack
                      of regional convergence in children/adolescents with ADHD,
                      which might be due to heterogeneous clinical populations,
                      various experimental design, preprocessing, statistical
                      procedures in individual publications. Our results highlight
                      the need for further high-powered investigations, but may
                      also indicate ADHD pathophysiology might rest in network
                      interactions rather than just regional abnormality.},
      cin          = {INM-7 / INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406 / I:(DE-Juel1)INM-1-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572) / HBP SGA2 -
                      Human Brain Project Specific Grant Agreement 2 (785907) /
                      SMHB - Supercomputing and Modelling for the Human Brain
                      (HGF-SMHB-2013-2017)},
      pid          = {G:(DE-HGF)POF3-572 / G:(EU-Grant)785907 /
                      G:(DE-Juel1)HGF-SMHB-2013-2017},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30790635},
      UT           = {WOS:000465050600001},
      doi          = {10.1016/j.neubiorev.2019.02.011},
      url          = {https://juser.fz-juelich.de/record/861112},
}