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@ARTICLE{Kneller:861357,
author = {Kneller, G. R. and Calandrini, V.},
title = {{S}elf-similar dynamics of proteins under hydrostatic
pressure—{C}omputer simulations and experiments},
journal = {Biochimica et biophysica acta / Proteins and proteomics
Proteins and proteomics [...]},
volume = {1804},
number = {1},
issn = {1570-9639},
address = {Amsterdam [u.a.]},
reportid = {FZJ-2019-01839},
pages = {56 - 62},
year = {2010},
abstract = {Different experimental techniques, such as kinetic studies
of ligand binding and fluorescence correlation spectroscopy,
have revealed that the diffusive, internal dynamics of
proteins exhibits autosimilarity on the time scale from
microseconds to hours. Computer simulations have
demonstrated that this type of dynamics is already
established on the much shorter nanosecond time scale, which
is also covered by quasielastic neutron scattering
experiments. The autosimilarity of protein dynamics is
reflected in long-time memory effects in the underlying
diffusion processes, which lead to a non-exponential decay
of the observed time correlation functions. Fractional
Brownian dynamics is an empirical model which is able to
capture the essential aspects of internal protein dynamics.
Here we give a brief introduction into the theory and show
how the model can be used to interpret neutron scattering
experiments and molecular dynamics simulation of proteins in
solution under hydrostatic pressure},
cin = {IAS-5 / INM-9},
ddc = {570},
cid = {I:(DE-Juel1)IAS-5-20120330 / I:(DE-Juel1)INM-9-20140121},
pnm = {899 - ohne Topic (POF3-899)},
pid = {G:(DE-HGF)POF3-899},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:19540369},
UT = {WOS:000272765200009},
doi = {10.1016/j.bbapap.2009.05.007},
url = {https://juser.fz-juelich.de/record/861357},
}