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@ARTICLE{Rosenberg:861491,
      author       = {Rosenberg, Jessica and Lechea, Nazim and Pentang, Gael N.
                      and Shah, N. J.},
      title        = {{W}hat magnetic resonance imaging reveals – {A}
                      systematic review of the relationship between type {II}
                      diabetes and associated brain distortions of structure and
                      cognitive functioning},
      journal      = {Frontiers in neuroendocrinology},
      volume       = {52},
      issn         = {0091-3022},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2019-01952},
      pages        = {79 - 112},
      year         = {2019},
      abstract     = {Due to its increasing prevalence, Type 2 diabetes mellitus
                      (T2DM) represents a major health challenge for modern
                      society. Despite it being of fundamental interest, only a
                      few MRI studies have conducted statistical analyses to draw
                      scientifically valid conclusions about the complex interplay
                      of T2DM and its associated clinical, structural, functional,
                      metabolite, as well as cognitive distortions. Therefore, a
                      systematic review of 68 manuscripts, following the PRISMA
                      guidelines, was conducted. Notably, although the
                      associations between imaging, clinical, and cognitive
                      variables are not fully homogeneous, findings show a clear
                      trend towards a link between altered brain structure and a
                      decline in cognitive processing ability. The results of the
                      review highlight the heterogeneity of the methods used
                      across manuscripts in terms of assessed clinical variables,
                      imaging, and data analysis methods. This is particularly
                      significant as, if the subjects’ criteria are not
                      carefully considered, results are easily prone to
                      confounding factors.},
      cin          = {INM-4 / JARA-BRAIN / INM-11},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / $I:(DE-82)080010_20140620$ /
                      I:(DE-Juel1)INM-11-20170113},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30392901},
      UT           = {WOS:000459526300007},
      doi          = {10.1016/j.yfrne.2018.10.001},
      url          = {https://juser.fz-juelich.de/record/861491},
}